Kidney Transplantation Clinical Trial
Official title:
Effects of Conversion From Sirolimus Oral Solution to Tablets in Renal Transplant Recipients.
The purpose of this study is to understand the pharmacokinetics of sirolimus tablets in different regimens in newly renal transplant patients, and the effect of dosage form conversion on the concentration of sirolimus in stable renal transplant patients. So that we can design a better tacrolimus or cyclosporine/sirolimus/steroid dose regimen for Taiwanese.
Sirolimus tablets will be available more than one year after the launch of sirolimus
solution. Most patients on sirolimus solution will use sirolimus tablet instead.
The purpose of this study is to understand the pharmacokinetics of sirolimus tablets in
different regimens in newly renal transplant patients, and the effect of dosage form
conversion on the concentration of sirolimus in stable renal transplant patients. So that we
can design a better tacrolimus or cyclosporine/sirolimus/steroid dose regimen for Taiwanese.
;
Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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