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NCT ID: NCT03374748 Completed - Clinical trials for Food Consumption Database Analysis

Examination of Meal Patterns in National Adult Nutrition Survey (NANS), Ireland

Start date: October 2008
Phase: N/A
Study type: Observational

This study is a secondary analysis of the dietary, phenotypic and demographic data collected within the National Adult Nutrition Survey (NANS), Ireland, to determine meal patterns using a variety of statistical methods.

NCT ID: NCT03374423 Completed - Clinical trials for Post-Mastectomy Chronic Pain Syndrome

Radiofrequency for Chronic Post-mastectomy Pain: is it Better to Target Intercostal Nerves or Corresponding Dorsal Root Ganglia?

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

neuropathic pain can occur following any surgical procedure on the breast ..

NCT ID: NCT03374371 Completed - Clinical trials for Staphylococcus Epidermidis Positive Blood Culture

Invasive Markers of Staphylococcus Epidermidis

SepiNGS
Start date: March 1, 2018
Phase:
Study type: Observational

The purpose of the study is to identify biomarkers allowing the distinction between invasive and non-invasive strains of Staphylococcus epidermidis. This distinction is important to determine if the patient is infected and, as a consequence, if an antibiotic treatment is required.

NCT ID: NCT03374163 Completed - Clinical trials for Infertility Due to Nonimplantation

Effect Of Intravenous IntralipidTherapyon Pregnancy Outcome in Women With History of Recurrent Implantation Failure Undergoing Intracytoplasmic Sperm Injection-Embryo Transfer Cycle: A Randomized Controlled Trial

Start date: January 1, 2015
Phase: Phase 2
Study type: Interventional

To evaluate the effect ofempiricintralipidinfusion therapy on pregnancy outcomes in patient withunexplained recurrentimplantation failure (RIF) undergoIntracytoplasmic sperm injection (ICSI).

NCT ID: NCT03373760 Completed - Clinical trials for Recurrent Squamous Cell Lung Carcinoma

Durvalumab and Tremelimumab in Treating Patients With Recurrent Stage IV Lung Cancer

Start date: November 30, 2017
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well durvalumab and tremelimumab works in treating patients with stage IV lung cancer that has come back after previous treatment. Monoclonal antibodies, such as durvalumab and tremelimumab, may interfere with the ability of tumor cells to grow and spread.

NCT ID: NCT03373370 Completed - Diagnosis Clinical Trials

Early Diagnosis of TTR Amyloidosis by Use of Molecular Biology

ADDITION
Start date: March 17, 2017
Phase:
Study type: Observational

Peripheral neuropathies are diseases that affect the nervous system outside the brain and spinal cord, their prevalence is 1% in the general population, the causes are extremely varied with more than 200 identified causes; the main ones are diabetes, excessive alcohol consumption and chemotherapy. They may be sometimes disabling but generally preserve autonomy. Transthyretin amyloidosis is a rare multisystematic hereditary disease with autosomal dominant transmission. They present usually as a peripheral neuropathies (FAP). They are due to a point mutation of the transthyretin gene (chr 18q). FAP is secondary to endoneurial amyloid deposits and are characterized by a slowly progressive sensory, motor and autonomic. FAP is the most severe hereditary polyneuropathy of the adult are irreversible and fatal within 5 to 12 years from onset. Most frequent mutation of TTR gene is located on the second exon; but more than 100 mutations have been reported. Prevalence of FAP is 1 per 1 million inhabitants. They have been reported until 1990s' in four endemic areas North of Portugal, Sweden, Japan and Majorca. In these areas, diagnosis is facilitated because of the stereotypical presentation : a length-dependent polyneuropathy with predominant involvement of thermal and pain sensations and autonomic dysfunction, early onset in the third decade and a predominant Met30 TTR mutation. Positive family history is frequent 85% (one of the parents is affected). Diagnosis requires detection of TTR mutation by molecular biology (blood sample) and characterization of amyloid deposit on labial salivary gland biopsy.

NCT ID: NCT03373253 Completed - Clinical trials for Depressive Disorder, Treatment-Resistant

Treatment-Resistant Depression Cohort in Europe

Start date: February 13, 2018
Phase:
Study type: Observational

The purpose of this study is to assess the participants socio-demographics and disease-related characteristics, long-term naturalistic treatment patterns and the clinical, social and economic outcomes of routine clinical practice in the treatment of participants with treatment-resistant depression (TRD) in a variety of European countries.

NCT ID: NCT03373188 Completed - Clinical trials for Pancreatic Adenocarcinoma

VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancer

Start date: December 15, 2017
Phase: Phase 1
Study type: Interventional

This randomized phase I trial studies how well anti-semaphorin 4D (anti-SEMA4D) monoclonal antibody VX15/2503 with or without ipilimumab or nivolumab work in treating patients with stage I-III pancreatic cancer that can be removed by surgery or stage IV colorectal cancer that has spread to the liver and can be removed by surgery. Monoclonal antibodies, such as anti-SEMA4D monoclonal antibody VX15/2503, ipilimumab, and nivolumab, may interfere with the ability of tumor cells to grow and spread.

NCT ID: NCT03372889 Completed - Clinical trials for Anterior Cruciate Ligament Injury

On-Q Catheter Caregiver Education

Start date: July 11, 2017
Phase: N/A
Study type: Interventional

The present study aims to compare caregiver satisfaction and efficacy between two modes of patient education materials (PEMs): media based and print based. The caregivers of patient's who undergo ACL (anterior cruciate ligament) reconstruction surgery and receive an On-Q Catheter pain block receive both a hand-out (print based PEM) and watch a short video (media-based PEM) describing how to care for their child's On-Q Catheter at home. Upon enrollment into the study, caregivers are randomly assigned to either first view the hand-out or the video, then complete a 10 questions standardized assessment of information that was presented in the PEMs. Caregivers are called the next day to assess caregiver satisfaction with the PEMs, which mode of PEM was more helpful to them, and how comfortable they felt managing their child's pain pump at home.

NCT ID: NCT03372837 Completed - Clinical trials for Assess the Efficacy and Safety of SyB L-0501 in Combination With Rituximab in Patients With Recurrent or Relapsed DLBCL

Phase III Study of SyB L-0501 in Combination With Rituximab to Treat Recurrent/Relapsed Diffuse Large B-Cell Lymphoma

Start date: January 15, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the efficacy of SyB L-0501 in combination with rituximab in patients with recurrent/relapsed diffuse large B-cell lymphoma.