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NCT ID: NCT03522571 Completed - Clinical trials for Altered Passive Eruption of Teeth

Experimental Gingivitis in Patients With Altered Passive Eruption

Start date: February 21, 2017
Phase: N/A
Study type: Interventional

Altered passive eruption (APE) is an anatomical condition that is frequently diagnosed in periodontal clinical practice, especially for the ever-increasing demand of patients for the aesthetic improvement of their smile. In addition to its aesthetic value, however, altered passive eruption could also affect gingival and periodontal health. In fact, in the case of plaque accumulation, the altered passive eruption (APE) is likely to be a predisposing factor for a more rapid progression of gingivitis with higher inflammation indexes (Angulated Bleeding Score - AngBs and Modified Gingival Index - mGI). Notwithstanding, even if gingivitis in patients with altered passive eruption is developed much more rapidly, thorough home oral hygiene and plaque control conduces to complete clinical recovery. Further studies with a large number of patients are required to confirm the correlation between altered passive eruption and periodontal diseases.

NCT ID: NCT03522415 Completed - Clinical trials for Moderately to Severely Active Rheumatoid Arthritis

Study of Safety and Efficacy of HLX01+MTX in Patients With Rheumatoid Arthritis

Start date: May 28, 2018
Phase: Phase 3
Study type: Interventional

To compare the efficacy between the HLX01 group and the placebo group through the proportion of subjects meeting the ACR20 improvement criteria for remission

NCT ID: NCT03522311 Completed - Clinical trials for Proliferative Diabetic Retinopathy

Surgical Outcomes for Proliferative Diabetic Retinopathy by Preoperative Glycemic Control and Renal Function

Start date: January 2013
Phase:
Study type: Observational

The surgical outcomes of 25-gauge vitrectomy for proliferative diabetic retinopathy has been evaluated by preoperative glycemic control and renal function

NCT ID: NCT03522194 Completed - Clinical trials for Left Ventricular Diastolic Dysfunction

Left Ventricular Diastolic Function During Anesthesia Induction

Start date: April 1, 2017
Phase:
Study type: Observational

Diastolic dysfunction is an important cause of hemodynamic instability in the perioperative field.Therefore this study aims to investigate the influence of existing diastolic dysfunction or deterioration of diastolic function on hemodynamic stability during induction of anesthesia and postoperative complications. The impact of different anesthetics on diastolic function is investigated.

NCT ID: NCT03522077 Completed - Clinical trials for Percutaneous Coronary Intervention

RAVE: Radial Artery Vascular Complication and Resource Utilization

Start date: May 9, 2018
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine if there is a reduction in time to hemostasis in subjects treated with SoftSeal®-STF hemostatic pad when used in conjunction with a vascular compression device after radial transcatheter procedure.

NCT ID: NCT03521687 Completed - Clinical trials for Central Centrifugal Cicatricial Alopecia

Apremilast in the Treatment of Central Centrifugal Cicatricial Alopecia (CCCA)

Start date: November 15, 2018
Phase: Phase 4
Study type: Interventional

This is a single-center, open-label clinical study to study the efficacy of apremilast in the treatment of mild to moderate central centrifugal cicatricial alopecia. The investigators hypothesize that the anti-inflammatory properties of apremilast may play a role in the decreasing scalp inflammation in patients with CCCA and may prevent further hair loss and potentially induce hair regrowth in patients with mild to moderate disease.

NCT ID: NCT03521492 Completed - Clinical trials for Early Childhood Caries, Vitamin D Deficiency

Vitamin D Status With Early Childhood Caries

Start date: October 30, 2017
Phase: N/A
Study type: Interventional

Studies that give people vitamin D supplements to prevent caries have found that vitamin D is effective at preventing the development of caries. The aim of Study: To determine if there is a relationship between vitamin D deficiency and the development of Early Childhood Caries (ECC).

NCT ID: NCT03521193 Completed - Migraine With Aura Clinical Trials

pLatelEts And MigRaine iN patEnt foRamen Ovale

LEARNER
Start date: February 15, 2018
Phase: N/A
Study type: Interventional

Migraine is a common, chronic neurovascular disorder characterized by attacks of severe headache, autonomic nervous system dysfunction and, in some patients, aura, and disabling neurological symptoms. Worldwide, migraine prevalence is as high as 18% in the general population. Increased frequency of patent foramen ovale (PFO) in migraineurs was first reported in 1998 in a case-control study. Since then, others have described a 60% prevalence of PFO in patients suffering from migraine with aura. The presence of a right-to-left shunt (RLS) is thought to be a potent trigger of migraine attacks, although the mechanism is unknown. Moreover, PFO closure has correlated with improved migraine symptoms in several retrospective uncontrolled studies. The aim of this single-center, prospective study is to assess the impact of PFO closure on migraine attacks over time together with evaluation of potential predictive risk factors.

NCT ID: NCT03521011 Completed - Clinical trials for Non Enhanced MSCT Abdomen in Diagnosis of Acute Abdomen

Non Enhanced MSCT In Diagnosis of Causes of Acute Abdomen Cases

Start date: April 1, 2018
Phase:
Study type: Observational

The acute abdomen is one of the most frequent causes for presentation to the emergency department. Imaging plays an important role for an accurate diagnosis, which in turn diminishes morbidity and mortality Jastaniah and Salih demonstrate optimum CT aspects and emphasize on the important features of CT for those patients presenting with an acute abdominal pain at the Emergency Department. The reported data by this study are based on the author working experience, which forms a continuous protocol adjustment process. The present study provides evidence that CT would result in definite diagnosis of patients with abdominal pain in terms of the detection of some urgent conditions . The acute abdomen may be defined generally as an intra-abdominal process causing severe pain and often requiring medical or surgical intervention. The acute abdomen is a frequent entity at the Emergency Department, the acute abdomen may be life threatening and so rapid diagnosis of patients presenting with acute abdominal pain is required . Diagnostic work-up with imaging can consist of plain X-ray, ultrasonography (US), computed tomography (CT) and even diagnostic laparoscopy. During the last decade, a trend towards increased use of computed tomography in patients with abdominal pain can be seen. In general, acute abdominal pain is responsible for about 10% of total number of patients visiting the emergency. Quick and precise diagnosis for the urgent cases is usually vital for treatment. Medical imaging is commonly used for the diagnosis of most acute abdomen pain. Abdomen and pelvis are reviewed by CT scan. Specifically, in cases of acute abdomen complain.

NCT ID: NCT03520998 Completed - Alzheimer Disease Clinical Trials

A Randomized Study to Assess the Safety of GRF6019 Infusions in Subjects With Mild to Moderate Alzheimer's Disease

Start date: April 16, 2018
Phase: Phase 2
Study type: Interventional

This study is evaluating the safety, tolerability, and feasibility of GRF6019, a plasma-derived product, administered as an intravenous (IV) infusion, to subjects with mild to moderate Alzheimer's disease.