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NCT ID: NCT04311255 Completed - Clinical trials for Best Regional Nerve Block for Creation of Surgical Brachiobasilic Fistula

Comparing the Efficacy and Safety of Ultrasound Guided Supraclavicular Block Combined With Either Intercostobrachialor Pec 11for Creation of Surgical Brachio-basilic Fistula in Chronic Renal Failure Patients on Hemodialysis

Start date: April 13, 2019
Phase: Phase 3
Study type: Interventional

In our study we are trying to reach to the more efficient us guided peripheral nerve block either intercosto-brachial or PPEC 11 that can be combined with us guided supraclavicular block to effectively anesthetise the surgical site for creation of brachio-basilic fistula as regarding onset of surgical anesthesia, adequacy of intra-operative anesthesia, the need for surgical wound infiltration, duration of postoperative analgesia and the failure rate of the fistulae.

NCT ID: NCT04311177 Completed - Clinical trials for Acute Respiratory Distress Syndrome

Losartan for Patients With COVID-19 Not Requiring Hospitalization

Start date: April 9, 2020
Phase: Phase 2
Study type: Interventional

This is a multi-center, double-blinded study of COVID-19 infected patients randomized 1:1 to daily losartan or placebo for 10 days or treatment failure (hospital admission).

NCT ID: NCT04310761 Completed - Clinical trials for Primary Maternal and Neonatal Outcomes; Assisted Reproductive Technology

Retrospective Comparison of Pregnancy Outcome of Infertile Patients After Fresh and Warmed Single Blastocyst Transfer From 2014 to 2018.

Start date: January 1, 2014
Phase:
Study type: Observational

The investigators retrospectively analysed the maternal and neonatal outcomes following a single fresh blastocyst transfer and a single warmed blastocyst transfer from procedures performed between 2014 and 2018 in a tertiary level university based fertility clinic.

NCT ID: NCT04310397 Completed - Clinical trials for Pathologic Stage IIIC Cutaneous Melanoma AJCC v8

Dabrafenib, Trametinib, and Spartalizumab for the Treatment of BRAF V600E or V600K Mutation Positive Stage IIIB/C/D Melanoma

Start date: January 29, 2020
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well dabrafenib, trametinib, and spartalizumab works in treating patients with BRAF V600E or V600K mutation positive stage IIIB/C/D melanoma, who do not achieve a pathologic complete response after 8 weeks of dabrafenib and trametinib treatment. Patients who achieve a pathologic complete response after 8 weeks of neoadjuvant dabrafenib and trametinib will receive adjuvant dabrafenib and trametinib. Dabrafenib and trametinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as spartalizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving dabrafenib, trametinib, and spartalizumab may help to control melanoma.

NCT ID: NCT04310267 Completed - Clinical trials for Skeletal Class 3 Malocclusion Due to Maxillary Deficiency

Three Levels of Force Application for Maxillary Protraction

MaxiProtr
Start date: June 5, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate dentoskeletal changes concomitant with different three levels of force application for maxillary protraction in growing patients with skeletal class 3 malocclusion.

NCT ID: NCT04310215 Completed - Clinical trials for Chondral or Osteochondral Lesion of Talus

Efficacy and Safety of Allogenic Stem Cell Product(CARTISTEM®) for Osteochondral Lesion of Talus

Start date: March 3, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of adding CARTISTEM®(allogenic umbilical cord blood-derived stem cell product) on microfracture, a currently standard treatment for OLT, in patients with talar chondral or osteochondral defect.

NCT ID: NCT04309994 Completed - Heart Attack Clinical Trials

Combined Use of a Novel Cardioplegic Formula With MPS® Versus Cardioplexol ® in Urgent Isolated CABG Using MiECC in Patients With Recent Acute Myocardial Infarction

Start date: February 1, 2010
Phase:
Study type: Observational

The goal of this study is to compare the two cardioplegia solutions (blood cardioplegia by means of MPS ® vs. Cardioplexol ®) regarding perioperative outcome and with special attention to cardiac markers in patients with a recent heart attack.

NCT ID: NCT04309656 Completed - Clinical trials for Multi-drug Resistant Tuberculosis

A Study in Two Panels of Healthy Adult Participants to Assess Single-Dose Immediate-Release and Single-Dose Dispersible Formulations of Pretomanid

Start date: January 14, 2020
Phase: Phase 1
Study type: Interventional

This is a single-dose, open-label, randomized, four-period, four-treatment, crossover study in healthy adult subjects.

NCT ID: NCT04309123 Completed - Clinical trials for Ventilator-Induced Diaphragm Dysfunction

Pilot Study of TransAeris® System in Surgical Patients at Risk of Prolonged Mechanical Ventilation

TRANSITION
Start date: March 30, 2020
Phase: N/A
Study type: Interventional

This study will be conducted as a pilot trial of the TransAeris system for the prevention and treatment of ventilator-induced diaphragm dysfunction (VIDD) in patients identified prior to surgery to be at greater risk of prolonged mechanical ventilation (PMV).

NCT ID: NCT04308941 Completed - Clinical trials for Intraocular Pressure and PROSE Lens

Tonometry Precision and Accuracy During PROSE Scleral Lens Wear: A Pilot Study

Start date: April 13, 2020
Phase: N/A
Study type: Interventional

The goal of this research is to determine the reproducibility of measurements of intraocular pressure (IOP) when a scleral lens is on the eye. The PROSE device (PD) is a specialized scleral lens that is filled with preservative-free saline and then applied to the eye in order to treat a variety of ocular conditions. The fit of the PROSE device is optimized to land gently on the conjunctival tissue overlying the sclera while completely vaulting the cornea and limbus without touch. Because the PROSE device vaults and therefore covers the cornea, measuring IOP during PROSE wear is challenging as traditional techniques rely on corneal contact (i.e. Goldmann tonometry, iCare, pneumatonometry, etc.). Measuring IOP before insertion and after removal of the PROSE device likely does not correspond to the true IOP when the PROSE device is actively on the eye. This is a prospective study of the reproducibility of three non-traditional means of IOP measurements: scleral tonopen, scleral pneumatonometry, and transpalpebral Diaton tonometer. Evaluating these means of measurements may be important for future studies investigating the effect of PROSE wear on intraocular pressure.