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NCT ID: NCT02614963 Not yet recruiting - Clinical trials for Effect of Clostridium Butyricum in Treating Irritable Bowel Syndrome

Effect of Clostridium Butyricum in Treating Irritable Bowel Syndrome

Start date: December 2015
Phase: Phase 4
Study type: Interventional

Clostridium Butyricum might be an effective drug in treating irritable bowel syndrome

NCT ID: NCT02614300 Not yet recruiting - Clinical trials for Non-cystic Fibrosis Bronchiectasis

The Role of Pulmonary Rehabilitation and Airways Clearance Techniques in the Multidisciplinary Management of Non CF Bronchiectasis

Start date: November 2015
Phase: N/A
Study type: Interventional

Pulmonary rehabilitation programs are part of the multidisciplinary treatment of some chronic respiratory diseases such as COPD (chronic obstructive pulmonary disease). Although clinical guidelines of other diseases such as non-cystic fibrosis bronchiectasis (nCFBE) discuss the benefits of these programs in quality of life and exercise tolerance, evidence of such intervention in nCFBE patients is insufficient. Longer studies are needed with larger sample sizes and optimized to maximize the response and maintain long-term benefits. The present study aims to examine the effects in exercise tolerance of a pulmonary rehabilitation program combined with respiratory physiotherapy in patients with nCFBE. It is a randomized controlled clinical trial with a total duration of 24 months. The intervention will be performed during 12 weeks and then will be a period of 12 months of maintenance. This is a multicenter study involving the following Hospitals: Hospital Clinic, Hospital la Plató and Hospital del Mar of Barcelona, Hospital Josep Trueta of Girona, Royal Infirmary of Edinburgh and Fondazione Maugeri di Lumezzane of Italy. Subjects will be randomized into three groups in a ratio (1: 1: 1) (1) Pulmonary Rehabilitation (2) Chest Physiotherapy and (3) Pulmonary Rehabilitation + Chest Physiotherapy. Hospital la Plató from Barcelona will be responsible for carrying out the Control Group. The primary endpoint will be the test of "endurance shuttle walk test".

NCT ID: NCT02613195 Not yet recruiting - Clinical trials for Evidence of Liver Transplantation

Clinical Trial of Hydrogen-Rich Celsior Solution Applied in Aging DBD Liver/Kidney Transplantation

HRCSDBD
Start date: January 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate whether hydrogen-rich Celsior solution improve the quality of aging grafts in liver/kidney transplantation.

NCT ID: NCT02610595 Not yet recruiting - Clinical trials for Idiopathic Membranous Nephropathy

Study on the Therapeutic Effect of TCM Treatment for MDR MN

Start date: December 2015
Phase: N/A
Study type: Interventional

To evaluate the effectiveness and safety of the Chinese medicine treatment for multiple drug resistance of MN patients with Jianpiyiqi and Huoxuejiedu Recipe.

NCT ID: NCT02607826 Not yet recruiting - Colorectal Cancer Clinical Trials

Short-term Starvation vs. Normal Diet Before Chemotherapy of Solid Tumors

Start date: November 2016
Phase: N/A
Study type: Interventional

Recent pre-clinical data provide strong evidence that short-term starvation before the administration of cytostatic drugs for the chemotherapy of solid tumors leads to significantly higher efficacy and lower toxicity levels. However, these findings have so far not been validated in patients. The aim of this trial is to provide first clinical evidence regarding the impact of pre-chemotherapeutic short-term starvation on response to therapy (primary endpoint). Additionally, progression-free survival, adverse events, and overall survival will be monitored (secondary endpoints). In perspective, short-term starvation before chemotherapy could represent a simple and secure way to improve both efficacy and tolerance of chemotherapies at low cost.

NCT ID: NCT02606474 Not yet recruiting - Clinical trials for Placenta Accreta in Placenta Previa Anterior

Placenta Accreta&Its Complications in Placenta Previa Cases

Start date: November 2015
Phase: N/A
Study type: Observational

Cases of previous cesarean with placenta previa anterior underwent cesarean section. Placenta accreta is diagnosed during cesarean section &confirmed by pathology. All complications are monitored in cases with placenta accreta and without.

NCT ID: NCT02604797 Not yet recruiting - Clinical trials for C.Delivery; Surgery (Previous), Gynecological

Analgesia Effects of Nalbuphine vs Sulfentanil

Start date: January 2016
Phase: N/A
Study type: Interventional

Cesarean section may result in great trauma and postoperative pain. Besides incision pain, uterine contraction pain is another source of postoperative pain after cesarean section. In clinical practice, a large amount of uterine contraction agent is routinely applied after cesarean section so as to promote involution of uterus and reduce postoperative hemorrhage, which also causes great uterine contraction pain. Acute pain is the risk factor of chronic pain, and may postpone the recovery from labour and influence the quality of life of parturient. Though various analgesia modules have been attempted, more than 20% parturients still experience severe postoperative pain, and pain management after cesarean section remains a challenge to anesthesiologists. This study aim to compare the effects of nalbuphine hydrochloride vs sufentanil citrate on patient-controlled intravenous analgesia after cesarean section.

NCT ID: NCT02601196 Not yet recruiting - Clinical trials for Women With Leiomyoma After at Least One Unsuccessful IVF Treatment

IVF Outcome Following Treatment With Ulipristal Acetate for Myomatous Uterus After at Least One IVF Failure

Start date: September 2016
Phase: Phase 4
Study type: Interventional

Hypothesis: After reviewing the relevant medical data the investigators assume that treating a woman with intramural fibroid not distorting the uterine cavity or mostly intramural with less than 50% submucosal component with Ulipristal Acetate (UPA) for a 13 weeks course would reduce the fibroid size and improve her chance for conceiving by IVF treatment. Materials & Methods: Study design: A proof of concept prospective not randomized study. The patients: About 20 women treated in the fertility and IVF unit after at least one IVF failure, with mostly intramural (IM) fibroid [class 2-5 by FIGO (International Federation of Gynecology and Obstetrics) classification system] in the size of >4 cm confirmed by Transvaginal ultrasound (TVUS) and diagnostic hysteroscopy. After US examination and diagnostic hysteroscopy to ascertain suitability for this study, the investigators will offer a course of 13 weeks treatment with UPA 5 mg per day. One month after cessation of treatment the investigators will perform another TVUS examination & diagnostic hysteroscopy plus endometrial biopsy in order to assess the endometrial & uterine status and will conduct an additional IVF cycle, using the same stimulation protocol undertaken during the immediate cycle previous to the UPA treatment course.

NCT ID: NCT02598024 Not yet recruiting - Clinical trials for Post-traumatic Stress Disorder (PTSD)

Treating Earthquake in Nepal Trauma (TENT) Trial 2016

TENT2016
Start date: March 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether two types of short-term trauma-focused therapies (individual Narrative Exposure Therapy and group-based Control-Focused Behavioural Treatment) are effective in the treatment of chronic PTSD in earthquake survivors of Nepal.

NCT ID: NCT02597842 Not yet recruiting - Clinical trials for Postoperative Nausea and Vomiting

Transcutaneous Electrical Acupoint Stimulation(TEAS) for Postoperative Nausea and Vomiting in Laparoscopic Operation

Start date: December 2015
Phase: N/A
Study type: Interventional

This is a single center, randomized, double-blinded, controlled clinical trial.The purpose of this study is to compare the effect of TEAS pretreatment with single acupoint or two acupoints for postoperative nausea and vomiting in patients undergoing laparoscopic operation.