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NCT ID: NCT02709304 Not yet recruiting - Clinical trials for Urinary Catheter Discomfort in Surgical Patients

Efficacy of Lidocaine Gel in Reducing Foley Catheter Discomfort in Surgical Patients

Start date: April 2016
Phase: Phase 4
Study type: Interventional

This study will evaluate whether lidocaine gel for urinary catheter insertion would decrease pain and discomfort associate with Foley catheters upon awakening from general anesthesia in the post anesthesia care unit. As a secondary objective, the study will evaluate bacterial colony counts from urine obtained from the surgical patients after insertion of the Foley catheter prior to prophylactic antimicrobial administration.

NCT ID: NCT02706444 Not yet recruiting - Clinical trials for Vascular Graft Anastomotic Stenosis

Drug-coated Balloon Versus Conventional Balloon Angioplasty in Hemodialysis Graft

Start date: March 2016
Phase: Phase 4
Study type: Interventional

To evaluate the role of DCB angioplasty for venous anastomotic stenosis of hemodialysis graft, investigators would like to perform randomized study comparing the results of drug- coated balloon angioplasty with conventional balloon angioplasty in the treatment in venous anastomotic stenosis of AVG in terms of patency.

NCT ID: NCT02705651 Not yet recruiting - Clinical trials for Pancreatic Neuroendocrine Tumors in MEN1

Non-functioning Pancreatic Neuroendocrine Tumors in MEN1: Somatostatin Analogs Versus NO Treatment

SANO
Start date: December 2019
Phase: Phase 3
Study type: Interventional

A.Background More than 90% of patients with multiple endocrine neoplasia type 1 (MEN1) develop multiple pancreatic neuroendocrine tumors (pNETs). These tumors are the most common cause for premature death in MEN1. While functioning pNETs must be treated to reduce or cure hormonal excess, the procedures for non-functioning pNETs are yet under discussion. Treatment ranges from watchful waiting to subtotal and total pancreatectomy. The latter may represent an "overtreatment", resulting in general complications and diabetic metabolic status. The effect of somatostatin analogues (SAs) has shown promising results with regard to progression of non-functioning duodeno-pancreatic NETs. Treatment with SAs is highly safe and effective, resulting in long-time suppression of tumor growth. B. Aim In this study of MEN1 patients with non-functioning pNETs, the benefits of somatostatin analogs" (SAs; group 1) compared to "no treatment" (group 2) will be analyzed with regard to progression (tumor growth; development of new [functioning and non-functioning] neuroendocrine tumors and regional/distant metastasis). C. Implementation Patients will either receive Somatostatin Analogs (SAs) or no treatment. The observation period will be 60 months. The increase of tumor size and development of new tumors or metastasis will be monitored.

NCT ID: NCT02704806 Not yet recruiting - Clinical trials for Immunol Feature in Circulation and Thromb in AMI Patients

Immunologic Analysis of Peripheral Blood and Aspirated Thromb In AMI Patients

ATAIA
Start date: April 2016
Phase: N/A
Study type: Observational

Researchers use FCM to analyze the immunol cell feature and its corresponding activation status, as well as the thromb aspirated through the thromb aspiration device in AMI patients

NCT ID: NCT02698813 Not yet recruiting - Clinical trials for Senescence Wrinkles, Acne, Pitting Scar

Safety Study of Filler Agent Composed of Umbilical Cord Mesenchymal Stem Cells and Hyaluronic Acid

Start date: December 2016
Phase: Phase 1
Study type: Interventional

The overall goal of this study is to evaluate the safety and exploratory efficacy of the injectable filler agent composed of umbilical cord mesenchymal stem cells and hyaluronic acid for the improvement of wrinkles, acne, pitting scar and so on.

NCT ID: NCT02696174 Not yet recruiting - Clinical trials for Health Care Quality, Access, and Evaluation

Effectiveness of A Health Microinsurance Scheme for Private Primary Care in Malaysia

HMI
Start date: April 2016
Phase: N/A
Study type: Interventional

This is the Phase 3 of a 3 phase study to determine the feasibility, acceptability and effectiveness of a health microinsurance scheme in improving health equity and clinical outcomes for private primary care (PPC) in Kuala Lumpur, Malaysia. This two-arm, pre-post, quasi-experimental trial consisted of utilizing a HMI scheme (experimental clinic) and normal OOP payments (control clinic) for 6 months. The HMI scheme enabled subscribed households to access a defined benefit package at a selected PPC for treatment and follow-up.

NCT ID: NCT02688686 Not yet recruiting - Clinical trials for Non-Small-Cell Lung Cancer With Bone Metastases

Safety and Efficacy of DC-CIK in Patients With Advanced Non-Small-Cell Lung Cancer With Bone Metastases

Start date: February 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this Phase I/II study is to evaluate the safety and efficacy of dendritic cells(DC) vaccine combined with cytokine-induced killer (CIK) cells in patients with Advanced Non-Small-Cell Lung Cancer with bone metastases. Experimental DC was transfected Ad5 vector coding mRNAs including suppressor of cytokine signaling (SOCS) 1, MUC1 and Survivin,are used for DC-based immunotherapy. Based on the results of our previously preclinical study with DC vaccine combined with CIK cells, the investigators plan to perform the clinical trial.

NCT ID: NCT02687425 Not yet recruiting - Clinical trials for Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Safety and Efficiency Study of Pioglitazone in Combination With Imatinib Mesylate to Treat Chronic Myelogenous Leukemia

SESPI
Start date: February 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and efficiency of adding pioglitazone to chronic phase chronic myelogenous leukemia patients having received imatinib mesylate who have acquired a stable molecular response but not complete molecular response.

NCT ID: NCT02686151 Not yet recruiting - Clinical trials for Ovarian Hyperstimulation Syndrome

The Letrozole Administration During Luteal Phase

Start date: December 2023
Phase: Phase 3
Study type: Interventional

To investigate the effect of letrozole in patients who have high risk of ovarian hyperstimulation syndrome (OHSS) after oocyte retrieval, the incidence of OHSS were calculated between letrozole group and supporting treatment group.

NCT ID: NCT02683460 Not yet recruiting - Clinical trials for Osteoarthritis, Patella Resurfacing

Patellar Resurfacing Under Subvastus Approach in Total Knee Arthroplasty

Start date: February 2016
Phase: N/A
Study type: Interventional

This study aims to compare the clinical results of patella resurfacing or not under subvastus approach in total knee arthroplasty. Even though the excellent results of total knee arthroplasty(TKA), there is persistent controversy over whether or not to replace the patella. Anterior knee pain continued to be a unsolved problem of TKA patients. Some surgeons always performed patella resurfacing during total knee arthroplasty but the others didn't do that. It's up to surgeon's preference. There were several studies of patellar resurfacing or not in TKA. But previous studies almost have been done under other approach, not a subvastus approach. This study prospectively randomized patients receiving bilateral TKA with patellar resurfacing or not in each knee. Patients preference and clinical results was investigated in both knee of same patients who received patellar resurfacing or not during minimum 2 year follow up.