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NCT ID: NCT04464590 Completed - Diagnostic Imaging Clinical Trials

Interest of a Systematic One-year Monitoring by 18F-FDG PET-CT

LYMPHOTEP1
Start date: January 1, 2009
Phase:
Study type: Observational

In the study, we aimed to characterize the role of FDG PET/CT surveillance at 12 months of malignant lymphoma in asymptomatic patients after a first complete remission and to define a rational follow-up strategy.

NCT ID: NCT04464473 Completed - Clinical trials for Transcranial Magnetic Stimulation

cTBS/fMRI Study of Hierarchical Control in the PFC

Start date: July 23, 2021
Phase: N/A
Study type: Interventional

The objective of this study is to examine the effect of transcranial magnetic stimulation (TMS) on the prefrontal cortex and posterior parietal cortex.

NCT ID: NCT04464356 Completed - Clinical trials for Transcatheter Aortic Valve Replacement

Application of Emergent Peripheral Mechanical Circulatory Support in Transcatheter Aortic Valve Replacement for 6 Patients

Start date: March 1, 2013
Phase:
Study type: Observational

Objective: To explore the experience of transcranial aortic valve replacement (TAVR) under emergency mechanical assisted circulation (MCS).Methods: A total of 6 patients who completed TAVR with the assistance of emergency MCS in the Second Affiliated Hospital of Zhejiang University School of Medicine from March 2013 to June 2019 were retrospectively analyzed.The management of perioperative mechanical assisted circulation, preoperative evaluation, intraoperative operation and postoperative situation of patients were summarized.

NCT ID: NCT04464161 Completed - Clinical trials for Intervertebral Disc Disorders With Radiculopathy, Lumbar Region

The Effects of Perioperative Nutritional Optimization on Blood Markers

Start date: July 20, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to see if taking an oral nutrition supplement (Ensure Nutrition Shake) before and after lumbar spine surgery affects blood tests related the nutritional status of patients. Patients with poor nutritional statuses who undergo elective lumbar spine surgery are at increased risk for complications and longer hospitalizations.

NCT ID: NCT04464083 Completed - Clinical trials for IOP Readings Before and After Accelerated Corneal Collagen Crosslinking (CXL)

IOP Measurements Using ORA After ACXL in Keratoconus

Start date: April 12, 2020
Phase:
Study type: Observational

The investigators measured IOP by Goldmann applanation tonometry(GAT) before and 6 months after accelerated 8 minutes CXL in using Avedro Kxl ,and correlated with corneal resistance factor(CRF)using ORA, AC angle and CCT using Scheimpflug imaging.

NCT ID: NCT04464057 Completed - Infant Clinical Trials

Safety and Effectiveness of Early Feeding After Bowel Anastomosis in Neonates or Infants

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

The study is primary designed to evaluate the safety and effectiveness of early feeding after bowel anastomosis, and observe the effect of early postoperative feeding on promoting postoperative rehabilitation and reducing parenteral nutrition

NCT ID: NCT04463888 Completed - Clinical trials for Rehabilitation, Tenodesis, Stroke, Internet of Things

A Smart Home-based Exoskeleton Robot System for Stroke Patients

Start date: August 19, 2020
Phase: N/A
Study type: Interventional

In the proposed study, the investigators assumed that high dose of repetitive motor task training using an exoskeleton robot-assisted system may provide benefits in motor shaping and greater brain priming for hand paresis of the stroke patients. Nevertheless, the amount of therapeutic activity with clinicians' guidance is often short of number in therapy sessions.Therefore, using Internet of Things (IoT), connected rehabilitation products and the data they generate that are a new trend of rehabilitation strategy for providing remote home-programs support. The specific aim of this study is to to explore the feasibility of introducing the rental services of a Smart Home-based Exoskeleton Robot System through the IoT business model. And the second purpose is to investigate the effects of applying the exoskeleton robotic device for tenodesisgrip training as a home-based treatment for chronic stroke patients.The expected outcomes of this research are to clarify the feasibility of using IoT business model for launching smart rehabilitation device rental service and the effects of application a high dosage of hand movement training as home program on motor and hand function for patients with chronic stroke.

NCT ID: NCT04463615 Completed - Clinical trials for Refractory Lymphoproliferative Disorder

Leflunomide for the Treatment of Relapsed or Refractory CD30+ Lymphoproliferative Disorders

Start date: May 5, 2021
Phase: Phase 2
Study type: Interventional

This trial studies how well leflunomide works for the treatment of patients with CD30+ lymphoproliferative disorders that have come back (relapsed) or do not respond to treatment (refractory). Leflunomide may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

NCT ID: NCT04463251 Completed - Clinical trials for Acute ST Segment Elevation Myocardial Infarction

Study to Evaluate the Effect on Parameters of Systemic Inflammation and Disease Outcomes and Safety of RPH-104 in Subjects With Acute ST-elevation Myocardial Infarction

Start date: December 7, 2020
Phase: Phase 2
Study type: Interventional

The goal of the study was to evaluate the effect of single administration of RPH-104 at 80 mg and 160 mg on parameters of systemic inflammation and outcomes of the disease in subjects with ST-segment elevation myocardial infarction (STEMI)

NCT ID: NCT04463212 Completed - Clinical trials for Reversible Cerebral Vasoconstriction Syndrome

Endothelial Dysfunction in Reversible Cerebral Vasoconstriction Syndrome

DESS
Start date: January 29, 2021
Phase:
Study type: Observational

Reversible Cerebral Vasoconstriction Syndrome (RCVS) is a syndrome described at the end of the 20th century. Generally, it has a benign course. It is revealed by acute headaches, in different circumstances such as sexual activity, physical exertion or emotional disturbances. But, in few cases, it might be complicated by seizure, stroke and subarachnoid haemorrhage. The diagnosis is confirmed on radiological examination, which shows diffuse cerebral vasoconstriction of brain vessel. It calls reversible because at three month, vasoconstriction disappears. Most cases occur during post partum or after serotoninergic/adrenergic drug use. The pathophysiology is unknown but a transient disturbance in the control of cerebrovascular tone by sympathic hyperactivity and/or endothelial dysfunction are suspected. The assessment of endothelial dysfunction in brain is possible with transcranial doppler. Chen et al. showed an impairment of vasodilatation post apnea induced called BHI on RCVS subjects compared with healthy control. BHI is a reflect of endothelial function in brain. Currently, investigators do not know if endothelial dysfunction occurred only in brain or if it may occur in systemic vessel. Some case reports talk about systemic complication such as kidney infarct or hepatic arterial vasospasm so a systemic vascular dysfunction may be suspected. In this study, researchers will study systemic endothelial function by measure of the pulse wave velocity during RCVS and after its recovering at 3 months, and compare it at healthy controls.