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NCT ID: NCT04654663 Completed - Clinical trials for Coronary Artery Occlusive Disease

Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB

Start date: December 7, 2020
Phase:
Study type: Observational

Retrospective data collection. The aim of this study is to determine the effect of preoperative sarcopenia index on postoperative pulmonary complications in elderly patients undergoing off-pump coronary artery bypass graft surgery.

NCT ID: NCT04654169 Completed - Clinical trials for Adhesive Capsulitis of the Shoulder

Suprascapular Nerve Block in Addition to Intra-articular Corticosteroid Injection in Adhesive Capsulitis

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Adhesive capsulitis is a disease that negatively affects a person's quality of life by causing severe pain and limitation in the movements of the shoulder joint in all directions. Conservative approaches including nonsteroidal anti-inflammatory drugs or oral corticosteroid usage and physiotherapy program are the first choice for the treatment. However, painful exercises usually prevent patients from fully participating in the physiotherapy program. For this reason, interventional procedures such as intra-articular corticosteroid injection (IAI) and suprascapular nerve block (SSNB) are preferred to be applied before the physiotherapy program. The aim of this study is to reveal both short and long-term effects of SSNB and IAI combination on pain, shoulder range of motion (ROM), disability, and quality of life in patients with adhesive capsulitis. It is hypothesized that the addition of SSNB to IAI results in greater improvements in pain, passive and active shoulder ROMs, disability, and quality of life.

NCT ID: NCT04652817 Completed - Clinical trials for Labia Majora Atrophy and Hypotrophy

Evaluation of the Efficacy and Safety of the Dermal Filler for Augmentation of Labia Majora.

Start date: November 11, 2019
Phase: N/A
Study type: Interventional

The study is an open-label uncontrolled single-center study for the evaluation of the Performance characteristics (efficacy and safety) of the dermal filler "MMI-22-04-2019" on the female genital area for the aesthetic, medicinal, functional and reconstructive indications.

NCT ID: NCT04652505 Completed - Clinical trials for Malignant Solid Neoplasm

Effect of the COVID-19 Public Health Crisis on the Mental Health and Physical Well-Being of Cancer Patients, the Coping With COVID Study

Start date: July 13, 2020
Phase:
Study type: Observational

This study determines how the threat of the coronavirus has affected the mental health and physical well-being of cancer patients seen at the psychiatric oncology clinic, and how they have coped with any related stress. Questionnaires that assess coping strategies and behaviors for decreasing disease transmission may help researchers create recommendations for future public health crises and pandemics.

NCT ID: NCT04652479 Completed - Clinical trials for Acquired Hyperinsulinemic Hypoglycemia

Avexitide Safety and Efficacy to Treat Acquired Hyperinsulinemic Hypoglycemia

Start date: June 21, 2021
Phase: Phase 2
Study type: Interventional

The primary goal of this study is to evaluate the safety and efficacy of two different dosing regimens of an investigational drug called Avexitide in treating low blood sugar in patients with Acquired Hyperinsulinemic Hypoglycemia.

NCT ID: NCT04652219 Completed - Clinical trials for Malignant Neoplasms of Digestive Organs

CART Therapy in GUCY2C-positive Digestive Tract Tumors

CART
Start date: October 10, 2020
Phase: Early Phase 1
Study type: Interventional

Ict-gc is an open, single-center study to evaluate the safety and efficacy of CAR-T-targeted therapy in patients with advanced gastrointestinal tumors.

NCT ID: NCT04651920 Completed - Clinical trials for Epithelial Ovarian Cancer

A Study on Association Between HR Genes and the HRD Status in Chinese Epithelial Ovarian Cancer

Start date: November 26, 2020
Phase:
Study type: Observational

The association between homologous recombination (HR) gene mutations and homologous recombination deficiency (HRD) status in Chinese epithelial ovarian cancer (EOC) patients is little known. This study would recruit 400 Chinese EOC patients with known targeted gene mutations via a multi-panel testing of 27 genes, including BRCA1/BRCA2. All patients accept evaluation of HRD model, which is based on the loss of heterozygosity (LOH), telomere allele imbalance (TAI) and large-scale state transitions (LST). The mutated genes, HRD score model and their relationship with the prognosis, would provide a full description of for the Chinese EOC patients, and a potential explanation of platinum-resistance in such population.

NCT ID: NCT04651608 Completed - Pediatric Cancer Clinical Trials

The Effect of Acupressure Chemotherapy-related Nausea Vomiting in Children

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

This study is carried out to evaluate and compare the efficiency of acupressure practice applied with pressure or sea-band and their placebo on managing the acute nausea-vomiting symptoms developing due to chemotherapy in pediatric oncology patients.

NCT ID: NCT04651595 Completed - Clinical trials for Efficacy of Caudal Block on Intra-operative Anal Sphincter Muscle Tone

Efficacy of Caudal Block on Intra-operative Anal Sphincter Muscle Tone and Post-operative Analgesia During Anal Sphincter Sparing Procedures Under General Anaesthesia

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

upplementing general anaesthesia with caudal analgesia in sphincter sparing procedures might be useful as it will provide a satisfactory combination of sphincter muscle tone preservation, good intraoperative and postoperative analgesia along with a reduction in the consumption of opioids and anaesthetic drugs. To the best of our knowledge, this anaesthetic technique was not tested in sphincter sparing procedures before.

NCT ID: NCT04651556 Completed - Clinical trials for Intraperitoneal Magnesium Sulphate in Laparoscope in Pediatrics

Intraperitoneal Magnesium Sulphate and Bupivacaine Versus Intravenous Analgesia in Laparoscopic Surgeries in Pediatrics

Start date: April 4, 2019
Phase: Phase 4
Study type: Interventional

The investigators are going to study the analgesic efficacy of intraperitoneal instillation of a combination of Magnesium sulphate with bupivacaine versus ordinary used parenteral analgesics for pain relief after laparoscopic surgeries in pediatrics.