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NCT ID: NCT05874297 Not yet recruiting - Clinical trials for Anatomic Stage III Breast Cancer AJCC v8

Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer

ONE
Start date: June 20, 2024
Phase: N/A
Study type: Interventional

This trial tests an online nutrition education program focused on decreasing nutrition-related side effects of chemotherapy in patients with breast cancer. Patients undergoing chemotherapy are at risk for complications such as diarrhea or constipation which can lead to poor nutritional intake and malabsorption of nutrients. This study is testing the effects of information delivered via the Cook for Your Life website in conjunction with standard clinical care to improve symptom management during chemotherapy treatment for breast cancer, which could serve as a new model for supportive oncology care.

NCT ID: NCT05874193 Not yet recruiting - Clinical trials for Relapsed/Refractory Multiple Myeloma

A Collaborative Community Effort Using Belantamab Mafodotin in Relapsed/Refractory Myeloma

COSTA
Start date: June 2024
Phase: Phase 2
Study type: Interventional

This is a research study to find out if a drug called belantamab mafodotin in combination with dexamethasone, a steroid, can be safely and effectively given in the community setting. Belantamab mafodotin (BLENREP) was approved in the US in August 2020 under an FDA program called accelerated approval. In November 2022, belantamab mafodotin was removed from the market because a study to further confirm its activity in relapsed/refractory multiple myeloma did not deliver a supporting result. However, this confirmatory study demonstrated that some patients may still benefit from treatment with belantamab mafodotin, and that this benefit can be long lasting. Belantamab mafodotin is often given at large academic medical centers every 3 weeks. This study will assess whether it is possible to administer belantamab in the community setting every 6 weeks. It is unknown if administering belantamab every 6 weeks versus every 3 weeks will result in improved safety and/or reduced efficacy.

NCT ID: NCT05869851 Not yet recruiting - Hip Dysplasia Clinical Trials

Developmental Dysplasia of the Hip: Observation vs. Bracing

Start date: April 2024
Phase: N/A
Study type: Interventional

Developmental dysplasia of the hip (DDH) is the most common childhood hip condition. When caught early, bracing is the most frequently used treatment; however, the brace can disrupt important mother-baby bonding time in the newborn period and present challenges to daily living. In babies with mild DDH, some studies have suggested that their hips may improve naturally as they grow and develop. This study will look at whether careful monitoring can be just as good as bracing for babies diagnosed with mild DDH less than 3 months of age, potentially avoiding unnecessary treatment. This will be the first study to look at this question with babies being treated at different hospitals in seven different countries, so the results will make an impact on children and families worldwide.

NCT ID: NCT05869578 Not yet recruiting - Clinical trials for Perioperative/Postoperative Complications

Registry of Anesthesia and Perioperative Medicine

RAMP
Start date: June 1, 2023
Phase:
Study type: Observational [Patient Registry]

To assess mortality and morbidity associated to anesthesia interventions

NCT ID: NCT05863949 Not yet recruiting - Clinical trials for Vitamin D Deficiency

Clinical Trial of Vit D and Calcium for Recurrent BPPV

Start date: July 2023
Phase: N/A
Study type: Interventional

Randomized double blind placebo controlled trial of vitamin D supplements, with or without calcium supplementation, versus placebo in reduction of recurrences in BPPV.

NCT ID: NCT05861557 Not yet recruiting - Clinical trials for Locally Advanced Head and Neck Squamous Cell Carcinoma

Neoadjuvant Radiotherapy Combined With Toripalimab for Locally Advanced Head and Neck Squamous Cell Carcinoma

Start date: May 20, 2023
Phase: Phase 2
Study type: Interventional

This is a phase II study. Twenty-three patients with locally advanced head and neck squamous cell carcinoma were planned to be enrolled to assess the efficacy and safety of neoadjuvant immunotherapy combined with radiotherapy.

NCT ID: NCT05860881 Not yet recruiting - Skin Cancer Clinical Trials

Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin)

SiroSkin
Start date: October 31, 2023
Phase: Phase 3
Study type: Interventional

01.21 SiroSkin is a phase 3, double-blind, multi-centre, parallel-arm, randomised, placebo-controlled trial to evaluate the use of topical 1% sirolimus in the chemoprevention of skin cancer, versus placebo, applied every night for 6 months in solid organ transplant recipients.

NCT ID: NCT05859984 Not yet recruiting - Clinical trials for Viral Upper Respiratory Tract Infection

To Evaluate the Clinical Efficacy and Safety of Recombinant Human Interferon ω Spray in Treatment of Viral Upper Respiratory Tract Infection in Children

Start date: May 2023
Phase: Phase 2
Study type: Interventional

To evaluate the clinical efficacy and safety of recombinant human interferon ω spray in treatment of viral upper respiratory tract infection in children aged by 3-12 years, and to explore the appropriate usage and dosage of the drug in treatment of upper respiratory tract infection caused by viruses.

NCT ID: NCT05854966 Not yet recruiting - Clinical trials for Acute Myeloid Leukemia, in Relapse

CPI-613 Given With Metformin in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)

Start date: July 2024
Phase: Phase 2
Study type: Interventional

The purpose of this research study is to find out what effects (the good and bad) the combination treatment of metformin and CPI-613 has in treating participants with acute myeloid leukemia or granulocytic sarcoma that has either returned after treatment or did not respond to treatment.

NCT ID: NCT05854576 Not yet recruiting - Clinical trials for Disorders of Calcium and Bone Metabolism

Markers of Metabolism and Vascular Access in ESRD

Start date: September 1, 2023
Phase:
Study type: Observational

Aim of the study is to determine the association of markers of mineral metabolism with vascular access out come (maturation, patency of vascular access[AVF,AVG])To verify the relationship between vascular access complication (AVF,AVG) and lower levels of 25(OH)D, higher levels of fibroblast growth factor 23 (FGF23) and serum calcium, phosphorus, parathyroid hormone (PTH) in patients with ESRD on regular hemodialysis.