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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT02163668
Other study ID # OUYogaStudy
Secondary ID
Status Completed
Phase N/A
First received June 9, 2014
Last updated June 13, 2014
Start date September 2009
Est. completion date April 2012

Study information

Verified date June 2014
Source University of Oklahoma
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Interventional

Clinical Trial Summary

This study examined the effects of 8 months of Yoga training on bone density and bone turnover markers in premenopausal women, ages 35-50 years. The style of Yoga used was power Yoga that involved postures with a jumping component. The investigators hypothesized that the Yoga intervention would result in beneficial improvements in bone turnover markers, by increasing the bone formation marker and decreasing the bone resorption marker.


Recruitment information / eligibility

Status Completed
Enrollment 47
Est. completion date April 2012
Est. primary completion date June 2010
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 35 Years to 50 Years
Eligibility Inclusion Criteria:

- participants had not been engaged in resistance training or in Yoga exercise for at least 12 months prior to the study

- did not have chronic back or joint problems or cardiovascular disease

- not taking antihypertensive drugs or any medication that affects bone density

- not taking hormonal contraception

- they self-reported having regular menstrual cycles.

Exclusion Criteria:

- body weight more than 300 pounds

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention


Related Conditions & MeSH terms


Intervention

Other:
Yoga Group
8 months of Yoga training

Locations

Country Name City State
United States Department of Health and Exercise Science, University of Oklahoma Norman Oklahoma

Sponsors (1)

Lead Sponsor Collaborator
University of Oklahoma

Country where clinical trial is conducted

United States, 

References & Publications (2)

Chan K, Qin L, Lau M, Woo J, Au S, Choy W, Lee K, Lee S. A randomized, prospective study of the effects of Tai Chi Chun exercise on bone mineral density in postmenopausal women. Arch Phys Med Rehabil. 2004 May;85(5):717-22. — View Citation

Phoosuwan M, Kritpet T, Yuktanandana P. The effects of weight bearing yoga training on the bone resorption markers of the postmenopausal women. J Med Assoc Thai. 2009 Sep;92 Suppl5:S102-8. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Change in bone mineral density from baseline to 8 months pre and post 8 months training No
Primary change in bone turnover markers pre and post 8 month intervention No
Primary change in tibia bone characteristics changes in volumetric bone mineral density and bone strength of the non-dominant tibia assessed by peripheral Quantitative Computed Tomography (pQCT) pre and post 8 month intervention No
Primary Changes in muscular strength Isotonic 1 repetition maximum (1RM) for 4 lower body and 2 upper body resistance exercises pre and post 9 month intervention No
Primary Change in arterial compliance Arterial compliance of the large and small arteries was assessed using Pulse Contour analysis. pre and post 8 month interventon No
Primary Change in Insulin-like Growth Factor-1 (IGF-I) and Insulin-like Growth Factor BP3 (IGFBP3) pre and post 8 month intervention No
Secondary Daily Calcium intake Calcium intake is a potential confounding variable. Participants were encouraged to increase their calcium intakes if found to be low before the intervention began. pre and post 8 month intervention No
Secondary Menstrual History This information was used to monitor menstrual characteristics to ensure they were still premenopausal at the post test. pre and post 8 month intervention No
Secondary Dietary intake Three day dietary logs were recorded by participants before the exercise intervention. They were analyzed for caloric intake and nutrient composition using the Diet Analysis Plus 9 software. At baseline at the same time as other outcomes, about 2 weeks before the beginning of the yoga training No
Secondary Change in physical activity levels Physical activity levels estimated by the bone-specific physical activity (PA) questionnaire to monitor their PA outside of the intervention pre and post 8 month intervention No
Secondary Change in body composition pre and post 8 month intervention No
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