Prevalence and Predictors of Osteoporosis in the Beijing's Urban Population

Osteoporosis Clinical Trial

Official title:

Prevalence and Predictors of Osteoporosis in the Beijing's Urban Population

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT01476150
• Other study ID #: CJFSRI-OP
• Status: Not yet recruiting
• Phase: N/A
• First received: November 15, 2011
• Last updated: November 22, 2011
• Start date: January 2012
• Est. completion date: March 2014

Study information

• Verified date: November 2011
• Source: China-Japan Friendship Hospital
• Contact: Huiqiong Zhou, MD., PhD.
• Phone: +86-10- 8420 5721
• Email: hqzhou[@]hotmail.com
• Is FDA regulated: No
• Health authority: China: Ethics Committee
• Study type: Observational

Clinical Trial Summary

1. To establish a BMD reference database of Beijing's urban population, China.

2. To determine the prevalences and risk factors of osteoporosis and osteopenia in Beijing's urban population, China.

3. To describe the 25OHD level and estimate the prevalence of vitamin D insufficiency and deficiency of Beijing's urban population, China.

4. Estimation of the prevalence of osteoporotic fracture (vertebral) in over age of 60 of Beijing's urban population, China.

Description:

With one of the biggest populations in the world, China was heavily suffered from osteoporosis. The prevalence of osteoporosis in China even is increasing fast in recent years, which are especially notable in urban population. This change maybe due to the conditions including rapid economic growth, increase in life expectancy, and changes in lifestyle. Studies in 1998 including 13 separately small samples (no more than 1000 people) from 9 provinces in China showed that the prevalence of osteoporosis and osteopenia were 5.3-6.2% and 5.8-11.2%, respectively. These estimates were higher by approximately 1% than those reported in 1995. In 2002, according to DEXA results in connection with population census in 2000, Xiaoguang Cheng et al. took a survey in 600 people who were separately studied in previously 10 research projects and find that patients with osteoporosis account for approximately 6.97% of the total China population.

Although these studies have documented a remarkable increase in the prevalence of osteoporosis in China, these estimations were all based on small samples. No risk factors related with osteoporosis and osteopenia, esp. hypovitaminosis D on osteoporosis and osteopenia, have been analyzed yet. So it is impossible to make any forecast of osteoporosis or give any instruction for intervention.

Thus this study designed to provide current and reliable data on the prevalence of osteoporosis and osteopenia and associated risk factors correlation coefficients in the Beijing's urban adult population.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 10000
• Est. completion date: March 2014
• Est. primary completion date: January 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 20 Years to 79 Years

Eligibility

Inclusion Criteria:

• 20 to 79 residents in urban Beijing, China.

Exclusion Criteria:

Study Design

Observational Model: Ecologic or Community, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Osteoporosis

Locations

Country	Name	City	State
China	China-Japan Friendship Hospital	Beijing	Beijing

Sponsors (2)

Lead Sponsor	Collaborator
China-Japan Friendship Hospital	Merck Sharp & Dohme Corp.

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	A BMD reference database of Beijing's urban population, China.		2 years	No
Secondary	The prevalences and risk factors of osteoporosis and osteopenia in Beijing's urban population, China.		2 years	No