Does Vibration Therapy Induce Higher Than Normal Bone Strains and Strain Rates Than Those Experienced During Habitual Daily Activities

Osteoporosis Clinical Trial

Official title: Measurement of Induced Strains in the Human Tibia During Vibration Therapy and Habitual Activities

Status Completed

Clinical Trial Summary

The overall aim of this study is to test the hypothesis that vibration exercise can induce higher than normal bone strains and strain rates than are experienced during habitual locomotor activities.

The investigators plan to study healthy young volunteers to:

1. Determine the relationship between tibial bone strain and

• the frequency and amplitude of vibration therapy

• a range of habitual locomotor activities;

2. Determine the transmission of vibrations during vibration therapy, in terms of

• amplitude attenuation and phase shift of positional coordinates and accelerations at anatomic landmarks along the lower leg and other skeletal sites

• the relationship between these and different frequencies and amplitudes of vibration therapy;

3. Determine the muscle power in the lower limb associated with various habitual locomotor activities and its relationship to the measured tibial bone strain.

The investigators subsequently hope to use the data captured in this experiment to develop a QCT-based finite element (FE) model of the human lower limb (tibia, fibula and foot). The investigators will then validate this model in relation to the characteristics (amplitude and phase shift) of the measured tibial bone strain and transmission of vibrations to the different anatomical landmarks during vibration therapy.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Osteoporosis
• Sprains and Strains

• NCT number: NCT01430858
• Study type: Interventional
• Source: Sheffield Teaching Hospitals NHS Foundation Trust
• Status: Completed
• Phase: N/A
• Start date: March 2011
• Completion date: December 2012