Osteoporosis Clinical Trial
Official title:
Cohort Study: Perceptual Urge Sensation
Over the past few years it has become clear that our understanding of bladder physiology is
inadequate to explain urge incontinence. This has forced us to re-evaluate what we know and
do not know about bladder function and dysfunction. This has led to the identification and
study of novel systems within the bladder that may contribute to abnormal sensations.
The investigators now suspect that the organic changes occurring in the bladder are not the
whole story. For one group of patients with pathological urge there is growing evidence
suggesting that there may be a strong psychological component. The idea now being put forward
is that normal afferent peripheral information is perceived as abnormal and excessive,
resulting in an increased desire to go to the bathroom: 'perceptual urge'. It is important to
identify this group of patients since it will direct their treatment towards more cognitive
approaches. Also, if such a psychological aetiology can be eliminated it would lead to a more
focused and effective management of peripheral pathology with surgery or pharmacology.
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