The Relationship Between Vitamin D, Fingernail Thickness and Bone Density

Osteoporosis Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00006196
• Other study ID #: NCRR-M01RR00036-0754
• Secondary ID: M01RR000036
• Status: Completed
• Phase: Phase 1
• First received: September 7, 2000
• Last updated: June 23, 2005

Study information

• Verified date: December 2003
• Source: National Center for Research Resources (NCRR)
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

Vitamin D deficiency is common in the elderly and contributes to the increased incidence of falls, hip fracture and depression in this population. An unknown number of elderly have vitamin D resistance resulting in a functional vitamin D deficiency state. Because there are no simple procedures or blood tests that identify vitamin D resistance, its prevalence and contribution to disability in the elderly is unknown. Our inability to screen for this condition precludes our ability to initiate and monitor treatment.

Previous studies indicate that fingernail thickness correlates with vitamin D status and may therefore provide a simple cost effective procedure to not only identify patients with vitamin D deficiency but also, those with vitamin D resistance. This procedure may also provide a way to monitor an individual's response to treatment.

This study is designed to demonstrate the association between fingernail thickness and vitamin D status.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 25 Years to 75 Years

Eligibility

Inclusion Criteria:

• females 25-75 years of age with no known bone disorders

Exclusion Criteria:

• history of vertebral fractures or nonvertebral fractures without trauma

• prescription medications for prevention of osteoporosis (including vitamin D other than multivitamin and estrogen)

• history of malignancy other than basal cell or squamous cell cancer of the skin

• use of steroids or anticonvulsants in the 6 months prior to enrollment

Study Design

Allocation: Randomized, Masking: Double-Blind, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Osteoporosis

Intervention

Drug:
• Vitamin D

Locations

Country	Name	City	State
United States	4488 Forest Park, Suite 201	St. Louis	Missouri

Sponsors (1)

Lead Sponsor	Collaborator
National Center for Research Resources (NCRR)

Country where clinical trial is conducted

United States,