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Clinical Trial Summary

Reduced intensity conditioning followed by allogeneic stem cell transplantation will result in mixed/complete donor chimerism and potentially alter the natural history and outcome of patients with non-malignant diseases.


Clinical Trial Description

This study is to determine the toxicity of administering a fludarabine/cyclophosphamide (Flu/CY) or busulfan (Bu)/Flu based conditioning regimen followed by allogeneic stem cell transplant (AlloSCT) in patients with non-malignant diseases. ;


Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01019876
Study type Interventional
Source Columbia University
Contact James Garvin, MD, PhD
Phone 212 305 5872
Email jhg1@columbia.edu
Status Recruiting
Phase Phase 2/Phase 3
Start date June 2002
Completion date May 2013

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