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Clinical Trial Summary

This clinical trial studies the clinical effectiveness of S53P4 bioactive glass (BAG) as a bacterial growth inhibiting bone graft substitute in a one-stage or two-stage surgical procedure for treatment of chronic long bone osteomyelitis.


Clinical Trial Description

In this prospective multicenter study, patients from two different university hospitals in the Netherlands were included. Treatment consisted of debridement surgery, implantation of S53P4-BAG, if necessary wound closure by a plastic surgeon and additional culture based systemic antibiotics. Primary outcome was eradication of infection based on clinical presentation, radiographic imaging and laboratory tests. Secondary analysis was performed on probable risk factors for treatment failure after S53P4-BAG implantation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04945434
Study type Interventional
Source Academisch Ziekenhuis Maastricht
Contact
Status Active, not recruiting
Phase N/A
Start date September 1, 2011
Completion date June 30, 2021

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