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Clinical Trial Summary

Osteomyelitis is described as infection and inflammation of the long bone or bone marrow, often due to an open wound, operation, or invasive trauma.1 It is invasive and involves hematogenous seeding or contiguous spread of the infectious organism


Clinical Trial Description

This disease can be classified by location of infection, extent of spread, chronicity, and source of infection.3,4 Osteomyelitis can be caused by a variety of organisms, most commonly gram-positive staphylococci. Osteomyelitis is associated with a high rate of relapse, high disease burden, and high health care costs.3 Following confirmation of disease via imaging and histopathologic examination, treatment consists of antibiotic therapy and, often, surgical intervention.3,5,6 Treatment with antibiotic therapy is often administered for 4-6 weeks when surgical intervention is not performed.6 Antibiotic selection should be guided by microbiology and antimicrobial susceptibilities.4 Thirty to sixty percent of osteomyelitis cases are caused by Staphylococcus aureus. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06096012
Study type Observational
Source Methodist Health System
Contact Bethany Brauer, MPH
Phone 214-947-4681
Email MHSIRB@mhd.com
Status Recruiting
Phase
Start date June 23, 2023
Completion date June 23, 2024

See also
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