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NCT05878548 Clinical Trial

Management of Combined Fracture Neck of Femur and Femoral Deformity in Osteogenesis Imperfecta Patient

Osteogenesis Imperfecta Clinical Trial

— OI  

Official title:
Management of Combined Fracture Neck of Femur and Femoral Deformity in Osteogenesis Imperfecta Patient

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05878548
Other study ID # NOFOI
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date August 1, 2023
Est. completion date April 1, 2024

Study information
Verified date January 2024
Source Assiut University
Contact Hesaham M Elbaseet, MD
Phone +2001007780689
Email drhesham20@aun.edu.eg
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

O.I with NOF fixed by Wagner technique and telescoping nail

Description:

osteogenesis imperfecta (Sillence Type IV) sustained neck of femur fracture after fall on ground. He had proximal femoral anterolateral bowing on top of inserted rod 4 years ago. He was treated with corrective osteotomy and intramedullary telescoping nail for deformed femur and Wagner technique to fix NOF fracture. One year after operation the patient gained satisfactory functional outcome with union of NOF fracture and correction of femoral deformity. This rare case illustrates the anticipated difficulties in managing neck of femur fracture in osteogenesis imperfect patients. The method of fixation with Wagner technique can achieve stable fixation for solid healing in fragility fractures like this and the least interference with telescoping nail insertion.

Recruitment information / eligibility
Status Recruiting
Enrollment 1
Est. completion date April 1, 2024
Est. primary completion date April 1, 2024
Accepts healthy volunteers No
Gender All
Age group 2 Years to 14 Years
Eligibility Inclusion Criteria: - OI Exclusion Criteria: - Not receiving Bisphosphonate

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• corrective osteotomy and intramedullary telescoping nail for deformed femur and Wagner technique to fix NOF fracture
corrective osteotomy and intramedullary telescoping nail for deformed femur and Wagner technique to fix NOF fracture

Locations
Country Name City State
Egypt faculty of medicine Assiut university Assiut

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

References & Publications (2)

Fralinger DJ, Kraft DB, Rogers KJ, Thacker MM, Kruse RW, Franzone JM. The Fate of the Bent Rod in Children With Osteogenesis Imperfecta. J Pediatr Orthop. 2023 Jul 1;43(6):e465-e470. doi: 10.1097/BPO.0000000000002409. Epub 2023 Apr 6. — View Citation

Hidalgo Perea S, Green DW. Osteogenesis imperfecta: treatment and surgical management. Curr Opin Pediatr. 2021 Feb 1;33(1):74-78. doi: 10.1097/MOP.0000000000000968. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary modified McKay's criteria hip function score the higher the score the better outcome graded into excellent, Good , Fair and Poor 1 year
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