Osteochondral Defect Clinical Trial
Official title:
A Pilot Study to Evaluate the Efficacy of BioCartilage® Micronized Cartilage Matrix in Microfracture Treatment of Osteochondral Defects of the Talus
The study was designed by the principal investigator, Dr. Andrea Veljkovic, and the St.
Paul's Hospital Foot and Ankle Research Group, who will conduct the study. The study is being
funded by Arthrex, Inc., the manufacturer of the Health Canada approved BioCartilage®
Micronized Cartilage Matrix.
The purpose of this study is to assess whether adding BioCartilage® to microfracture
treatment of osteochondral defects of the talus improves osteochondral healing as well as
improving pain and function.
Efficacy will be assessed primarily by outcomes scores as measure by the Ankle Osteoarthritis
Scale (AOS) at the baseline and at multiple post-op followup visits. Additional outcomes
scores will also be administered to compare general health and foot function between the two
groups at baseline and at multiple post-op followup visits. X-rays and MRI will be used to
assess the osteochondral healing rate.
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