Reliability of Measuring Walking-related Performance Fatigability Using Six Minute Walk Test in Persons With Knee Osteoarthritis

Osteoarthritis Clinical Trial

Official title:

Reliability of Measuring Walking-related Performance Fatigability Using Six Minute Walk Test in Persons With Knee Osteoarthritis

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04530266
• Other study ID #: FUI/CTR/2020/6
• Status: Recruiting
• Phase: N/A
• Start date: August 28, 2020
• Est. completion date: December 28, 2020

Study information

• Verified date: August 2020
• Source: Foundation University Islamabad
• Contact: Muhammad Osama, PhD*
• Phone: 03325540436
• Email: osamadpt[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Evidence has shown that knee osteoarthritis causes an increase in base of support and a decrease in stride length and gait velocity which results in an increase in energy expenditure during walking. This increase in energy cost of walking is suggested to result in walking related performance fatigability. However, fatigue is not commonly considered in the clinical settings in term of neither assessment nor management of knee osteoarthritis. One common tool used to evaluate walking relate performance is six minute walk test and the purpose of this study is to determine the reliability of using six minute walk test to determine walking related performance fatigability in persons with knee osteoarthritis.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 80
• Est. completion date: December 28, 2020
• Est. primary completion date: December 28, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 40 Years to 70 Years

Eligibility

Inclusion Criteria:

• Age 40-70 years

• Knee OA with history not less than three months.

• Radiological evidences of grade III or less on Kellgren classification.

• Knee pain on VNRS no more than 8/10.

Exclusion Criteria:

• Neuromuscular conditions that may lead to fatigue such as multiple Sclerosis

• Signs of serious pathology (e.g., malignancy, inflammatory disorder, infection).

• History of trauma or fractures in lower extremity.

• Signs of lumbar radiculopathy or myelopathy.

• History of knee surgery or replacement.

• Patients on intra-articular steroid therapy within two months before the commencement of the study.

• Impaired skin sensation and renal function.

Related Conditions & MeSH terms

• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Diagnostic Test:
• Six minute walk test
Assessment of walking related performance fatigability using six minute walk test

Locations

Country	Name	City	State
Pakistan	Foundation University Institute of Rehabilitation Sciences.	Islamabad	Federal

Sponsors (2)

Lead Sponsor	Collaborator
Foundation University Islamabad	Hasselt University

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Assessment of walking related performance fatigability using six minute walk test		Day 1
Primary	Assessment of walking related performance fatigability using six minute walk test		Day 2