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NCT01063504 Clinical Trial

Teriparatide for Improved Knee Prosthesis Fixation

Osteoarthritis of the Knee Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01063504
Other study ID # PTHKnee
Secondary ID
Status Completed
Phase Phase 2
First received February 4, 2010
Last updated June 17, 2013
Start date February 2010
Est. completion date June 2013

Study information
Verified date June 2013
Source University Hospital, Linkoeping
Contact n/a
Is FDA regulated No
Health authority Sweden: Ministry of education and research
Study type Interventional

Clinical Trial Summary

The investigators will study how well knee joint prostheses become fixed to the bone when patients get teriparatide, compared to placebo. Measurements will use high resolution 3D radiography (radiostereometry, RSA).

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date June 2013
Est. primary completion date June 2013
Accepts healthy volunteers No
Gender Both
Age group 60 Years to 80 Years
Eligibility Inclusion Criteria:

- Osteoarthritis of the knee planned for prosthesis surgery

Exclusion Criteria:

- Poor health, drugs affecting bone metabolism.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Intervention

Drug:
• teriparatide

Locations
Country Name City State
Sweden Motala hospital Motala

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Linkoeping

Country where clinical trial is conducted

Sweden, 

Outcome
Type Measure Description Time frame Safety issue
Primary Migration as measured by RSA maximal total point motion. 2 years No
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