Osteoarthritis of the Knee Clinical Trial
Official title:
Intraarticular Ozone Therapy for Pain Control in Osteoarthritis of the Knee
The purpose of this study is to determine whether an intraarticular injection of Ozone into the knee joint is an effective therapy for pain control in patients with osteoarthritis of the knee.
Ozone, as a gas made of three atoms of oxygen with a cyclic structure, has been used as a
medical therapy from the mid ninetieth century. Today, this therapy is a recognized modality
in many European and Latin American nations for orthopedic problems, infections, ischemic
diseases, and skin problems. However, despite of this wide use internationally, there is
minimal mention of this treatment modality in the Anglo-American literature.
The present is the first of a series of studies planned to scientifically test the
effectiveness of ozone as a main-stream therapy, introducing it to the Anglo-American
literature. In this first study we will check whether intraarticular injections of Ozone
into the knee joint are effective as a therapy for pain control in patients with
osteoarthritis of the knee.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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