Osteoarthritis of the Knee Clinical Trial
Official title:
Comparative Study of Olive Oil With Piroxicam Gel in Osteoarthritis of the Knee
this is a randomized double blinded trial which is conducted to measure the efficacy of topical virgin olive oil on osteoarthritis of knee that will be done in contrast to standard piroxicam gel.
application of herbal product has old history in therapy of human diseases. olive oil is one
of the important diet in Iran which its efficacy in reducing of rheumatic pains was pointed
out by Avicenna in 10th century. Nevertheless, its efficacy is not confirmed by scientific
study.
in this double blinded study, 200 patients with diagnosed osteoarthritis of knee will be
recruited that will randomly be assigned in piroxicam or olive oil group. the piroxicam gel
or olive oil will be repackaged in anonymous tubes, which only recognizable via codes. the
patients or visiting clinicians will be unaware of content of tubes. the final assessor will
be blind to groups and interventions.
the efficacy of therapies will be evaluated by means of WOMAC and PGs standard
questionnaires.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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