Physical Therapy Prior to Total Knee Replacement

Osteoarthritis of the Hip Clinical Trial

Official title:

Effect of Physical Therapy on Grade 3 or 4 Knee Osteoarthritis

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT02279277
• Other study ID #: Austin2014
• Status: Not yet recruiting
• Phase: N/A
• First received: October 6, 2014
• Last updated: October 28, 2014
• Start date: October 2014

Study information

• Verified date: October 2014
• Source: Rothman Institute Orthopaedics
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

In this study, the investigators are investigating the effects of physical therapy (PT) for treating high grade knee osteoarthritis (OA) in patients that are candidates for total knee replacement. Through the examination of patient outcomes, such as pain, stiffness, and physical function, the investigators will determine if PT prior to total knee replacement is an effective treatment in a patient with high grade OA.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 148
• Est. primary completion date: October 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. Knee osteoarthritis (Kellgren-Lawrence grade 3 or 4) confirmed via standing AP radiograph

2. Surgical candidate for TKA, having had a least a 3 months of pain affecting ADL's unresponsive to conservative treatment consisting of AT LEAST one non-narcotic medication AND one injection (corticosteroid or series of viscosupplementation). Injection must not have been administered within 6 weeks of start of PT trial

3. Prior knee surgery from arthroscopies, meniscal surgery and ligament reconstruction

Exclusion Criteria:

1. Anyone who received physical therapy in the last 6 months

2. Inability to walk unaided for >1 block

3. Currently engaged in regular PT or a regular home exercise program

4. Prior knee arthroplasty

5. Prior knee surgery for trauma, tumor and osteotomy

6. Injection given within 6 weeks of starting therapy

7. Patients using daily narcotic medications within prior 6 weeks

Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Osteoarthritis
• Osteoarthritis of the Hip
• Osteoarthritis, Hip

Intervention

Behavioral:
• Supervised physical therapy program prior to total knee replacement surgery

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Rothman Institute Orthopaedics

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Range of Motion following Total Knee Replacement		6 weeks	No
Secondary	Patient reported perception of pain following total knee replacement		6 weeks	No
Secondary	Return to functional activities following total knee replacement		6 weeks	No