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Clinical Trial to Evaluate the Efficacy and Safety of MegaCarti^® in Knee Cartilage Defects

Osteoarthritis, Knee Clinical Trial

Official title:
A Clinical Trial to Evaluate the Efficacy and Safety of Cartilage Regeneration in the Use of MegaCarti^® in Patients With Knee Joint Cartilage Injury: Multicenter, Independent Evaluator-subject Blinded, Microfracture-comparative, Randomized Clinical Study

Clinical Trial Summary

Subjects aged 50 to 65 years with knee cartilage defects will undergo microfracture treatment for cartilage regeneration and MegaCarti^® will be applied.

Clinical Trial Description

The MegaCarti^® is the decellularized allogeneic cartilage and acts as a cover after bone marrow stimulation to prevent the loss of blood clots and induces cartilage regeneration by assisting in the location of stem cells derived from bone marrow. To evaluate cartilage regeneration, the study group is compared with the microfracture group alone through MOCART evaluation at 48 weeks after treatment for cartilage regeneration. In addition, a biopsy is performed to evaluate the formation of hyaline cartilage and the area ratio of regenerated cartilage is measured. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06249828
Study type Interventional
Source L&C Bio
Contact
Status Recruiting
Phase N/A
Start date January 22, 2024
Completion date April 30, 2025
View Details
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