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Study on the Safety and Tolerance of Mesenchymal Stem Cells Mediated by Arthroscopy in Patients With Osteoarthritis

Osteoarthritis, Knee Clinical Trial

Official title:
A Single-Arm Clinical Study on the Safety and Tolerance of Human Umbilical Cord Mesenchymal Stem Cells Mediated by Arthroscopy in Patients With Stage II-III Knee Osteoarthritis

Clinical Trial Summary

The goal of this clinical trial is to evaluate the safety and tolerability of human umbilical cord mesenchymal stem cells mediated by arthroscopy in patients with knee osteoarthritis. This experiment proposes to enroll 18-22 patients. The experimental drug is human umbilical cord mesenchymal stem cells.

Clinical Trial Description

This study adopts a design for a single-dose increasing, single-center, randomized, placebo-controlled trial to explore the safety, tolerance and preliminary efficacy of the single-dose administration of human umbilical cord mesenchymal stem cells mediated by arthroscopy in patients with knee osteoarthritis, as well as to provide a basis for the subsequent clinical study of drug delivery plans. The experimental process of this study is divided into four stages: screening period, baseline period, study treatment and safety observation period, follow-up period. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06082440
Study type Interventional
Source First Affiliated Hospital of Wannan Medical College
Contact Weijie He
Phone 15178538969
Email heweijie613@163.com
Status Recruiting
Phase Early Phase 1
Start date November 22, 2023
Completion date January 10, 2026
View Details
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