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NCT05678049 Clinical Trial

Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid

Osteoarthritis, Knee Clinical Trial

Official title:
Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05678049
Other study ID # UMFCluj
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date January 15, 2023
Est. completion date December 15, 2024

Study information
Verified date January 2023
Source Universitatea de Medicina si Farmacie Iuliu Hatieganu
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The research study aims to evaluate the synovial fluid to highlight the presence of possible micropolymers (micro/nanoplastics) in order to better understand the pathophysiology of joint degenerative processes. For patients with liquid under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physician. The investigators want to use this liquid for Microscopic and Spectrophotometric evaluation.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 50
Est. completion date December 15, 2024
Est. primary completion date December 15, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria: - arthritis of the knee with liquid aspiration recommendation - age >18 years Exclusion Criteria: --refusal of the patient to participate -age<18 years

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Synovial fluid analysis
For patients with knee under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physicians. After making the evacuation we will want to use this liquid for Microscopic and Spectrophotometric evaluation

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Universitatea de Medicina si Farmacie Iuliu Hatieganu

Outcome
Type Measure Description Time frame Safety issue
Primary microplastics evaluation with spectrophotometry and optic microscopy immediately after liquid extraction
Primary nanoplastics evaluation with spectrophotometry and optic microscopy immediately after liquid extraction
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