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Intra-articular Injection of MSC-derived Exosomes in Knee Osteoarthritis (ExoOA-1) — ExoOA-1  

Osteoarthritis, Knee Clinical Trial

Official title:
A Phase I Study Aiming to Assess Safety and Efficacy of a Single Intra-articular Injection of MSC-derived Exosomes (CelliStem®OA-sEV) in Patients With Moderate Knee Osteoarthritis (ExoOA-1)

Clinical Trial Summary

The study aim to evaluate safety of exosomes (sEVs) from allogeneic mesenchymal stromal cells delivered by an intra-articular injection in the knee of patients with mild to moderate symptomatic osteoarthritis. The sEVs will be produced in a GMP-facility. We expect to enrolle 10 patients in this phase 1 trial and the follow-up will be up to 12 months.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05060107
Study type Interventional
Source Universidad de los Andes, Chile
Contact Jose Matas, MD
Phone +56 2 26183347
Email jmatas@clinicauandes.cl
Status Not yet recruiting
Phase Phase 1
Start date October 5, 2021
Completion date October 5, 2023
View Details
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