Osteoarthritis, Knee Clinical Trial
Official title:
Radial Versus Focused Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis : A Randomized Control Trial
Radial versus Focused Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis : A Randomized Control Trial
Background Knee Osteoarthritis (OA) is the most prevalent of the chronic rheumatic diseases
and is a leading cause of pain and disability in most countries worldwide. The treatment
methods for knee OA are diverse for patients with mild or moderate osteoarthritis (OA).
Biomechanical intervention, physical therapy and exercise, medication, and intra-articular
injections (both corticosteroid and hyaluronic acid) are recommended.
Recent studies have suggested that extracorporeal shock wave therapy is an effect treatment
method for the knee OA. Based on the propagation pattern of the wave, extracorporeal shock
wave therapy can be classified into two main modalities: focused and radial shock wave
therapy. However, no previous study compared the effect of radial versus focused type of
extracorporeal shock wave on symptoms and functions in patients with symptomatic knee OA.
Therefore, the purpose of our study was to compare the effects of focused and radial shock
wave therapy on patients with knee OA. Design: Randomized control trial Setting: Outpatient
rehabilitation clinic in our hospital. Population:100 patients with mild and moderate knee OA
Methods: Patients were randomly assigned to receive three sessions of either focused or
radial shock wave therapy at 1-week intervals. The extracorporeal shock wave will be applied
to the patellofemoral and tibiofemoral borders and the subchondral bone of the medial tibia
condyle of the affected knee joint. The intensities that were used during focused shock wave
therapy (0.20 mJ/mm 2 ) and radial shock wave therapy (3 bar) were comparable. The patients
were evaluated at baseline and at 1, 4, and 8 weeks and 6 nmonths after the final shockwave
treatment. The primary outcome measure was visual analogue scale. The secondary outcome
measures were Western Ontario and McMaster Universities Osteoarthritis Index, the knee joint
ROM, and sonographic findings and six-minute walk test (6MWT) will be performed. A linear
mixed model with repeated measures was used to compare each outcome measure between the two
groups.
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