Osteoarthritis, Knee Clinical Trial
Official title:
Positive and Negative Affects Among Osteoarthritis Patient
Osteoarthritis (OA) is a common and debilitating disease, For the majority of patients, pain
in OA is episodic in nature.
The experience of pain is generated or modified by nociception, neuropathic symptoms,
psychological and personality factors, genetic influences, past painful experiences, comorbid
conditions, and expectations related to future pain Previous studies have shown psychological
well-being has been significantly associated with disability in patients with OA, and anxiety
has been found to be associated with knee pain in women.
Previous studies also found that there are large interindividual differences among persons
with knee osteoarthritis (OA) with respect to psychological function.
Psychological strengths and weaknesses are evaluated among new patient with osteoarthritis
presented to joint replacement clinic, to facilitate our understanding of those patients
need, and correlating with their radiological and clinical findings. Psychological strengths
and weaknesses, positive and negative affects are evaluated in form of questionaires.
Reference:
Adaptation to disability: Applying selective optimization with compensation to the behaviors
of older adults with osteoarthritis.
MAM Gignac, C Cott, EM Badley - Psychology and aging, 2002
Analgesic effects of multisensory illusions in osteoarthritis C Preston, R Newport -
Rheumatology, 2011
Psychological factors and their relation to osteoarthritis pain BL Wise, J Niu, Y Zhang, N
Wang, JM Jordan… - Osteoarthritis Cartilage. , 2010 - Elsevier
Introduction:
Osteoarthritis (OA) is a prevalent painful condition that may cause disability among older
adults (Cruz-Almeida et al., 2013). Psychological traits and emotional states of patients
were found to be correlated with symptoms of OA and daily functioning of patients
(Cruz-Almeida et al., 2013; Dezutter et al., 2015).
The experience of pain is generated or modified by nociception, neuropathic symptoms,
psychological and personality factors, genetic influences, past painful experiences, comorbid
conditions, and expectations related to future pain. Previous studies have shown
psychological well-being has been significantly associated with disability in patients with
OA, and anxiety has been found to be associated with knee pain in women.
Previous studies also found that there are large interindividual differences among persons
with knee osteoarthritis (OA) with respect to psychological function.
Aim of project:
This research is trying to find out what psychological strengths or factors could attenuate
the chronic pain of knee OA patients. The purpose of the study is to find psychological
evidences that may be used in the future to help chronic pain patients for improving their
daily functioning and well-being.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03895489 -
Effectiveness of the Journey Total Knee Arthroplasty Versus Two Standard of Care Total Knee Arthroplasty Prostheses
|
N/A | |
| Completed |
NCT03660943 -
A Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee Pain
|
Phase 3 | |
| Completed |
NCT04531969 -
Comparison of Outpatient and Inpatient Spa Therapy
|
N/A | |
| Completed |
NCT02848027 -
Correlating the Osteoarthritic Knee Microenvironment to Clinical Outcome After Treatment With Regenexx®SD Treatment
|
Phase 3 | |
| Completed |
NCT05160246 -
The Instant Effect of Kinesiology Taping in Patients With Knee OA
|
N/A | |
| Recruiting |
NCT06080763 -
Biomechanics and Clinical Outcomes in Responders and Non-Responders
|
||
| Completed |
NCT03643588 -
The Comparison of HYAJOINT Plus and Hyalgan Hyaluronan Supplement for Knee Osteoarthritis Pain
|
N/A | |
| Active, not recruiting |
NCT05100225 -
Efficacy and Safety Trial of PTP-001 (MOTYS) for Symptomatic Knee Osteoarthritis
|
Phase 2 | |
| Active, not recruiting |
NCT04061733 -
New Hydroxyethyl Cellulose Hydrogel for the Treatment of the Pain of Knee Arthrosis
|
N/A | |
| Completed |
NCT04051489 -
A Novel Smartphone Application for "Smart" Knee Osteoarthritis Trials
|
||
| Recruiting |
NCT05546541 -
Epidemiology and Nutrition
|
||
| Recruiting |
NCT05447767 -
Prediction AlgoriThm for regeneraTive Medicine Approach in knEe OA: New Decision-making Process Based on Patient pRofiliNg
|
Phase 2 | |
| Not yet recruiting |
NCT04448106 -
Autologous Adipose Tissue-Derived Mesenchymal Stem Cells (AdMSCs) for Osteoarthritis
|
Phase 2 | |
| Not yet recruiting |
NCT03225911 -
Effect of a Lateral Wedge Insole and Simple Knee Sleeve in Individuals With Knee Osteoarthritis
|
N/A | |
| Completed |
NCT05070871 -
A Clinical Trial Investigating the Effect of Salmon Bone Meal on Osteoarthritis Among Men and Women
|
N/A | |
| Completed |
NCT05703087 -
Positive Cueing in Knee Arthroplasty.
|
N/A | |
| Not yet recruiting |
NCT06042426 -
Effects of Perioperative Intravenous Dexamethasone in Clinical Outcomes After Total Knee Arthroplasty in a Hispanic Population
|
Phase 4 | |
| Completed |
NCT02881775 -
Immediate Effects of rTMS on Excitability of the Quadriceps With Knee Osteoarthritis
|
N/A | |
| Completed |
NCT02944448 -
A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee
|
Phase 2 | |
| Completed |
NCT02901964 -
Effect of Strengthening the Hip Abductor in Patients With Knee Osteoarthritis: Randomized Controlled Trial
|
N/A |