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Multicenter Bone and Joint Health Study — MOST  

Osteoarthritis,Knee Clinical Trial

Official title:
Multicenter Osteoarthritis Study (MOST) Second Renewal

Clinical Trial Summary

The purpose of this study is to investigate opportunities for prevention and treatment of knee osteoarthritis (OA) by evaluating potentially modifiable risk factors for disease and poor pain and physical function outcomes especially among those with early or mild knee symptoms. The goal of the study is to find novel strategies to prevent disease at an early stage and to limit the impact of disease once it has occurred.

Clinical Trial Description

MOST study participants in the "Existing Cohort" (3,026 subjects) were enrolled in the original study in 2003-2005. Surviving Existing Cohort participants without end-stage knee osteoarthritis will be asked to participate in the 144-, 152-, 160- and 168-month follow-up contacts. In addition, in 2016-2018 the cohort will be enriched by the recruitment of an additional 1,500 "New Cohort" participants with early or mild knee symptoms. The goal of the study is to find novel strategies to prevent disease at an early stage. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03033238
Study type Observational
Source University of California, San Francisco
Contact
Status Completed
Phase
Start date January 2003
Completion date December 2020
View Details
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