Osteoarthritis, Knee Clinical Trial
Official title:
Radiofrequency For The Treatment Of Chronic Knee Pain Following Total Knee Arthroplasty: A Double-Blind Randomized Controlled Pilot Study
Chronic knee osteoarthritis (OA) is one of the most common diseases with increasing
prevalence in advanced age. Knee OA results in movement restriction, sleep disturbance, and
disability. Total knee arthroplasty (TKA) is employed often in the symptomatic treatment of
knee OA. It has been estimated that 3.4 million TKAs will be performed in the year 2030 in
the United States alone. Many studies report rewarding outcomes for patients, but other
research shows there are many patients that remain dissatisfied post-arthroplasty.
The purpose of this study is to evaluate whether genicular radiofrequency ablation can
relieve chronic post-arthroplasty knee pain.
Chronic knee osteoarthritis (OA) is one of the most common diseases with increasing
prevalence in advanced age. Knee OA results in movement restriction, sleep disturbance, and
disability. Total knee arthroplasty (TKA) is employed often in the symptomatic treatment of
knee OA. It has been estimated that 3.4 million TKAs will be performed in the year 2030 in
the United States alone. Many studies report rewarding outcomes for patients, but other
research shows there are many patients that remain dissatisfied post-arthroplasty.
As the prevalence of knee arthroplasty increases, so does the frequency of revisions. It has
been found that 20% of patients reporting painful knee arthroplasties were not able to be
diagnosed with a specific cause and were therefore referred to a pain specialist.
Pharmacologic therapy and non-surgical interventions are often employed with minimal benefit
to the patient's level of disability as indicated by clinical evidence.
Genicular radiofrequency ablation seems to be a safe, effective and minimally invasive
therapy for chronic knee OA patients who have had a positive diagnostic block. No study has
determined whether genicular radiofrequency ablation can relieve chronic post-arthroplasty
knee pain. The investigators propose to examine the effect of genicular radiofrequency
ablation in chronic post-arthroplasty knee pain in patients who respond positively to
diagnostic nerve blocks.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03895489 -
Effectiveness of the Journey Total Knee Arthroplasty Versus Two Standard of Care Total Knee Arthroplasty Prostheses
|
N/A | |
| Completed |
NCT03660943 -
A Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee Pain
|
Phase 3 | |
| Completed |
NCT04531969 -
Comparison of Outpatient and Inpatient Spa Therapy
|
N/A | |
| Completed |
NCT02848027 -
Correlating the Osteoarthritic Knee Microenvironment to Clinical Outcome After Treatment With Regenexx®SD Treatment
|
Phase 3 | |
| Completed |
NCT05160246 -
The Instant Effect of Kinesiology Taping in Patients With Knee OA
|
N/A | |
| Recruiting |
NCT06080763 -
Biomechanics and Clinical Outcomes in Responders and Non-Responders
|
||
| Completed |
NCT03643588 -
The Comparison of HYAJOINT Plus and Hyalgan Hyaluronan Supplement for Knee Osteoarthritis Pain
|
N/A | |
| Active, not recruiting |
NCT05100225 -
Efficacy and Safety Trial of PTP-001 (MOTYS) for Symptomatic Knee Osteoarthritis
|
Phase 2 | |
| Active, not recruiting |
NCT04061733 -
New Hydroxyethyl Cellulose Hydrogel for the Treatment of the Pain of Knee Arthrosis
|
N/A | |
| Completed |
NCT04051489 -
A Novel Smartphone Application for "Smart" Knee Osteoarthritis Trials
|
||
| Recruiting |
NCT05546541 -
Epidemiology and Nutrition
|
||
| Recruiting |
NCT05447767 -
Prediction AlgoriThm for regeneraTive Medicine Approach in knEe OA: New Decision-making Process Based on Patient pRofiliNg
|
Phase 2 | |
| Not yet recruiting |
NCT04448106 -
Autologous Adipose Tissue-Derived Mesenchymal Stem Cells (AdMSCs) for Osteoarthritis
|
Phase 2 | |
| Not yet recruiting |
NCT03225911 -
Effect of a Lateral Wedge Insole and Simple Knee Sleeve in Individuals With Knee Osteoarthritis
|
N/A | |
| Completed |
NCT05070871 -
A Clinical Trial Investigating the Effect of Salmon Bone Meal on Osteoarthritis Among Men and Women
|
N/A | |
| Completed |
NCT05703087 -
Positive Cueing in Knee Arthroplasty.
|
N/A | |
| Not yet recruiting |
NCT06042426 -
Effects of Perioperative Intravenous Dexamethasone in Clinical Outcomes After Total Knee Arthroplasty in a Hispanic Population
|
Phase 4 | |
| Terminated |
NCT02615522 -
Prospective Post Market Clinical Follow-Up of the Primary Knee Endoprosthesis BPK-S Integration
|
||
| Not yet recruiting |
NCT02854176 -
Somatosensory Stimulation in Knee Osteoarthritis
|
Phase 2 | |
| Completed |
NCT02881775 -
Immediate Effects of rTMS on Excitability of the Quadriceps With Knee Osteoarthritis
|
N/A |