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Steroids, Hyaluronic Acid or Platelet Rich Plasma Versus Placebo for the Knee Osteoarthritis — KIT  

Osteoarthritis, Knee Clinical Trial

Official title:
Intraarticular Injections of Steroids, Hyaluronic Acid or Platelet Rich Plasma Versus Placebo for the Knee Osteoarthritis

Clinical Trial Summary

This study investigates clinical outcome and imaging outcome parameters after intraarticular injection of steroids, platelet-rich-plasma (prp), hyaluronic acid or placebo in patients with early osteoarthritis of the knee joint.

Clinical Trial Description

Osteoarthritis of the knee joint is a very common disease in middle aged and elderly patients. This study evaluates the efficiency of different commonly used substances for intraarticular, non-operative treatment in early stages of this disease. 120 patients receive an fluoroscopic guided injection in the knee joint: 30 patients get injection with steroids 30 patients get injection with prp 30 patients get injection with hyaluronic acid 30 patients get injection with placebo (iopamiro contrast media) Primary outcome: - clinical outcome (pain using numeric rating scale) - Magnetic Resonance imaging (cartilage defects etc.) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02776514
Study type Interventional
Source Balgrist University Hospital
Contact
Status Completed
Phase Phase 2
Start date February 2016
Completion date November 2020
View Details
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