Osteoarthritis, Knee Clinical Trial
Official title:
A Controlled Surveillance of the Osteoarthritic Knee Microenvironment With Regenexx® SD Treatment
The primary objective of this study is to determine the levels of proteins and/or cellular components of the synovial fluid that are indicative of microenvironment phenotypes of the osteoarthritic knee compared to unilateral unaffected joints pre-injection to 6 weeks post-Regenexx® SD treatment.
The primary objective of this study is to determine the levels of proteins and/or cellular
components of the synovial fluid that are indicative of microenvironment phenotypes of the
osteoarthritic knee compared to unilateral unaffected joints pre-injection to 6 weeks
post-Regenexx SD treatment (day 0).
Secondary objective is an evaluation of possible direct and/or indirect associations between
the measured levels of proteins and/or cellular components of the synovial fluid in the
osteoarthritic knee joint with the administration of the Regenexx SD treatment. The secondary
objective will include MRI evidence of cartilage repair; incidence of post-operative
complications, adverse events, re-injections, and surgical intervention; change in pain score
and use of pain medications.
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