The Use of Bone Growth Stimulators for Osteoarthritis of the Knee.

Status Completed

Clinical Trial Summary

The hypothesis of this study is that since osteoarthritis of the knee is primarily a bone disease where the joint changes are secondary, and bone growth stimulators function to decrease intraosseous venous congestion and remodel bone, then there is a potential benefit for the treatment of osteoarthritis of the knee with bone growth stimulators.

Clinical Trial Description

The hypothesis of this study is based on the knowledge that osteoarthritis of the knee is primarily a bone disease, and the joint changes are secondary. Bone growth stimulators function to alleviate intraosseous venous congestion through the process of bone remodeling. The working hypothesis is that alleviation of intraosseous venous congestion leads to improved delivery of nutrition to the tissue to support the health of the bone with improvement in biomechanics leading to clinical improvement. Venous congestion is measured with intraosseous pressure. Additional objective evidence of biomarkers of bone metabolism as well as measurements of subjective questionnaires can provide evidence of benefit. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03476382
Study type	Interventional
Source	Coastal Carolinas Integrated Medicine
Contact
Status	Completed
Phase	N/A
Start date	April 9, 2018
Completion date	November 15, 2018

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