Could HRV be a Valuable Predictor for CPAP Adherence?

OSA Clinical Trial

Official title: If Heart Rate Variability Can Predict Continuous Positive Airway Pressure Acceptance and Compliance for Patients With Obstructive Sleep Apnea ?

Status Recruiting

Clinical Trial Summary

This study aim to evaluate if the improvement of heart rate variability for the continuous positive airway pressure titration night can predict the short and long term continuous positive airway pressure adherence for patients with moderate to severe OSA.

Clinical Trial Description

Heart rate variability (HRV) represents autonomic regulation and had been used in varies situation, especially the associated with cardiovascular outcomes and psychological diseases. HRV was also well known associated with the severity of obstructive sleep apnea (OSA) and could be improved after adequate treatments for OSA. Continuous positive airway pressure (CPAP) is the first choice of treatment for OSA and had been proved to able to improve HRV in OSA patients. However, the CPAP adherence is always problematic. Many CPAP predictors had been well documented but the HRV is never evaluated to be a potential predictor of CPAP adherence.

Therefore, this study will evaluate the changes of HRV for polysomnography (PSG) night, for CPAP titration night to see if the changes of HRV in the CPAP titration night could predict CPAP adherence for OSA patients in Taiwan. ;

Related Conditions & MeSH terms

• Adherence, Patient
• Autonomic Dysfunction
• Autonomic Nervous System Diseases
• OSA
• PAP
• Primary Dysautonomias

• NCT number: NCT03721445
• Study type: Observational [Patient Registry]
• Source: Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
• Contact: Mei-Chen Yang, MD
• Phone: 886-66289779
• Email: mimimai3461@gmail.com
• Status: Recruiting
• Start date: October 2, 2018
• Completion date: March 31, 2021