Oral Health Clinical Trial
Official title:
A Pilot Study of a Commercially-available Oil Rinse Product (PerioPull™) on Markers of Dental Health
The primary purpose of this study is to evaluate the impact of a commercially-available oil rinse product (PerioPull™) on parameters of dental health among a sample of adults. PerioPull™ is commercially available and sold primarily from clinicians' offices. A 12-week pilot study will be conducted to achieve the purpose of this study. The research team hypothesizes that PerioPull™ will improve a variety of validated markers of dental health that are commonly used in clinical practice.
Patients that suffer from dental health issues often have a deeper than normal pocket depth. These pockets can become filled with infection causing bacteria causing inflammation around the tooth leading to periodontal disease. The current recommendations are to brush with Sensodyne, use a special mouthwash, do not brush as hard, or use an electric toothbrush. PerioPull™ is a natural oil rinse formula to support overall oral/gum health, tooth stains, and natural teeth whitening. This formula contains specific nutrients that have been previously studied and shown to be efficacious in oral health These actions do not have any known side effects, which present an advantage over standard dental treatments with fluoride, chlorhexidine, hydrogen peroxide and other chemicals. This oil rinse formula is a commercially available product sold primarily from physicians' offices. As indicated in the ingredient list provided below, PerioPull™ includes Medium Chain Triglycerides (C8, C10, C12) (from coconut oil), Bixa orellana (Annatto) Seed Extract (GG-Gold®), Natural Mint Flavor, Bromelain, Ubiquionone, Delta Tocotrienols. The proposed study is a 12-week pilot study of PerioPull™. Eligible participants will be recruited from within the clinical practice of the periodontist. Study outcomes will consist of parameters of dental health among a sample of adults. These outcomes will be collected during a dental visit and assessed at baseline, six weeks, and at the conclusion of the 12-week clinical trial. Oral samples that are obtained during clinical visits will be sent to lab utilized by participating clinical practices for analysis of study outcomes. The outcomes in this clinical trial have been studied in previous clinical trials among dental patients. One oral sample at each of the three study visits is all that is required to collect outcomes. All study outcomes will be measurements and testing during three dental visits spaced 6 weeks apart. These are typical assessments in routine clinical practice. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06099574 -
A Study on the Oral Health Status of Pregnant Women With Gestational Diabetes and Its Correlation With Oral Flora
|
||
| Completed |
NCT00299598 -
Clinical Study of Antibacterial Nanoparticles Incorporated in Composite Restorations
|
Phase 2 | |
| Completed |
NCT00651248 -
Evaluation of Salivary Flow and Buffer Capacity Associated to Aged People's Oral Health
|
N/A | |
| Completed |
NCT05046210 -
The Effectiveness of Lay Health Advisors Strategy Intervention on Aborigines Elderly Oral Care Education
|
N/A | |
| Active, not recruiting |
NCT05124587 -
Prediction for Critical Outcomes of Patients With COVID-19
|
||
| Completed |
NCT03480516 -
Comparison of Caries Arrested & Prevented Among SDF, NaF Varnish and Combination in Children
|
N/A | |
| Recruiting |
NCT04140929 -
Oral Health Improvement for Nursing Home Residents Through Delegated Remotivation and Reinstruction
|
N/A | |
| Completed |
NCT05330793 -
The Effects of an Oral Probiotic Intervention With or Without a Novel ADP-1 Toothpaste
|
N/A | |
| Completed |
NCT04289337 -
Double-blind Clinical Trials of Probiotic Products in Oral Health.
|
N/A | |
| Not yet recruiting |
NCT06073392 -
Cluster RCT on the Effect of the Topics Number in Oral Health Educational Video Among Preschool Children.
|
N/A | |
| Completed |
NCT00103493 -
Oral Health Education Program
|
Phase 3 | |
| Enrolling by invitation |
NCT06080672 -
The Effect of Disclosing Dental Plaque on Plaque Index and Gingival Index in Faculty of Dentistry Students
|
N/A | |
| Completed |
NCT05755152 -
Fruit-based Chewing Gums for Improving Oral Health
|
N/A | |
| Completed |
NCT05515510 -
Acceptance and Efficacy of a Digital Application Among Parents to Control Early Childhood Caries
|
N/A | |
| Completed |
NCT03587428 -
Effect of Two Toothpastes on Bacteria in Saliva
|
N/A | |
| Active, not recruiting |
NCT01514552 -
The Use of Functional Confections in Promoting Oral Health
|
Phase 1 | |
| Enrolling by invitation |
NCT06124222 -
Prosthetic Rehabilitation and Its Influence on Masticatory Performance and QoL in Patients Treated for HNC
|
N/A | |
| Completed |
NCT05695443 -
Oral Health in Prison: a Study on Improving Prisoners' Oral Health
|
N/A | |
| Completed |
NCT03141554 -
The Effect of Oral Antiseptic Gargles on the Oral Cavity Microbiome
|
Phase 4 | |
| Completed |
NCT03376022 -
Attitudes and Knowledge of Oral Health Among Nursing Personnel
|