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Oral Cavity Disease clinical trials

View clinical trials related to Oral Cavity Disease.

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NCT ID: NCT06381505 Not yet recruiting - Oral Cavity Disease Clinical Trials

RetracTOR/ Retractor for Image Guided Trans-Oral Surgery

Start date: May 15, 2024
Phase:
Study type: Observational

This study aims to demonstrate that a polymer retractor functions the same as a standard metal retractor used during endoscopy and throat surgery. The retractor is the device that holds the mouth open so the surgeon can easily access the mouth and throat. For example, this study aims to confirm that the mouth is held open the same amount with a polymer retractor as it is with a metal retractor. Benchtop experiments have demonstrated that the metal and polymer retractor's function the same, and thus this study will use this in patients.

NCT ID: NCT05912335 Completed - Local Anesthesia Clinical Trials

Clinical Efficiency of Xanthan Hydrogels Containing Local Anesthetics Encapsulated in Nanostructured Lipid Carries

Start date: June 2, 2021
Phase: Phase 1
Study type: Interventional

In a crossover, randomized, placebo-controlled, double-blind study, 40 volunteers will receive the following formulations: hydrogels containing LAs (local anesthetic) - lidocaine and prilocaine (both at 2.5%) encapsulated in CLN (XAN-CLN) or not (XAN-CLN ), EMLA (topical anesthetic available on the market) and placebo hydrogel. The formulations will be applied for 2 minutes, bilaterally on the palatal mucosa (first premolar region), in two distinct sessions. Soon after removal of the topical formulation, an AL will be performed at the region using 0.3 mL of anesthetic solution at an injection speed of 1 mL/min. Pain resulting from needle insertion and LA injection will be measured using two visual analog scales (VAS).

NCT ID: NCT05911750 Recruiting - HPV Infection Clinical Trials

Prevalence and Clinical Implications of HPV Infection in Male IBD Patients

PAPIMALE
Start date: February 12, 2023
Phase:
Study type: Observational

The study aims at describing the prevalence of Human Papillomavirus (HPV) infection in anal and oral samples of men with Inflammatory Bowel Disease (IBD) and detecting risk factors for the infection.

NCT ID: NCT05267938 Completed - Oral Cavity Disease Clinical Trials

Microneedle Pretreatment as a Strategy to Improve the Effectiveness of Topical Anesthetics Formulations

Start date: August 1, 2019
Phase: Phase 1
Study type: Interventional

A randomized, crossover, double-blind, two-sessions clinical trial with 30 male volunteers was performed to access pain of local anesthesia after using a topical anesthetic associated or not with prior application of microneedles to the palatal mucosa region

NCT ID: NCT03855397 Completed - Oral Cavity Disease Clinical Trials

Pain and Safety of Microneedles in Oral Cavity

Start date: January 16, 2018
Phase: N/A
Study type: Interventional

A randomized, crossover, double-blind, placebo-controlled, one-session clinical trial with 30 male volunteers was performed to access pain and safety of microneedle topical application in different regions of the oral cavity.