TLR-9 Antagonism in Steroid Resistant Optic Neuritis

Status Completed

Clinical Trial Summary

Although idiopathic steroid resistant optic neuritis is very uncommon, there is no established treatment protocol for such patients. Toll like receptors (TLRs) especially TLR-9 has been shown to play a role in the pathogenesis of optic neuritis. This small case series aims to determine whether immunomodulators directed specifically at TLR-9(i.e. TLR-9 antagonism)play any role in improving the visual function in such patients.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01424735
Study type	Interventional
Source	Sudhalkar Eye Hospital
Contact
Status	Completed
Phase	N/A
Start date	July 2006
Completion date	May 2010

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