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Effect of Opioid-free Anesthesia on PostOperative Nausea and Vomiting in Patients Undergoing Video-assisted Thoracoscopic Surgery — OFA-PONV  

Opioid Use Clinical Trial

Official title:
The Effect of Opioid-free Anesthesia on PostOperative Nausea and Vomiting in Patients Undergoing Video-assisted Thoracoscopic Surgery: a Single-center Randomized Controlled Study

Clinical Trial Summary

This study aimed to verify whether an Opioid-free Anesthesia (OFA) could effectively reduce the incidence of PONV after thoracoscopic-assisted surgery compared with standard general anesthesia (OA) regimens.

Clinical Trial Description

Postoperative Nausea and Vomiting (PONV) is one of the most common complications after general anesthesia, which significantly reduces postoperative comfort and satisfaction of patients perioperatively. Meta-analysis showed that Opioid-free Anesthesia (OFA) significantly reduced the risk of postoperative PONV events in patients undergoing gynecology, breast, and abdominal surgery compared with standard general anesthesia (OA). The main hypothesis of the study is that an OFA could reduce the incidence of PONV in patients after thoracoscopic-assisted surgery than OA. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05411159
Study type Interventional
Source Beijing Chao Yang Hospital
Contact Yan Xiang, M.D.
Phone +8601058231330
Email yanxiang9991@163.com
Status Recruiting
Phase N/A
Start date June 7, 2022
Completion date December 31, 2024
View Details
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