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A Bioavailability and Safety Study of Probuphine Versus Sublingual Buprenorphine in Patients With Opioid Dependence — PRO-810  

Opioid Dependence Clinical Trial

Official title:
A Single Cross-Over, Open-Label Study of the Relative Bioavailability of Probuphine Versus Buprenorphine Sublingual Tablets at Steady State in Patients With Opioid Dependence

Clinical Trial Summary

This study will measure the amount of buprenorphine found in the blood after taking sublingual buprenorphine tablets versus after implantation with 4 Probuphine (buprenorphine implants).

Clinical Trial Description

This is an open-label study intended to evaluate the relative bioavailability of 4 Probuphine implants versus 16mg QD sublingual buprenorphine, as determined by plasma BPN AUC(0-24), during 24 hours at steady state. This study will also provide open-label safety and tolerability data in patients treated with Probuphine. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00768482
Study type Interventional
Source Titan Pharmaceuticals
Contact
Status Terminated
Phase Phase 3
Start date September 2008
Completion date December 2008
View Details
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