Local Anesthesia and Analgesics in Endodontic Pain — LAAEP  

Odontalgia Clinical Trial

Official title: Local Anesthesia and Analgesics in Post-Operative Endodontic Pain

Status Withdrawn

Clinical Trial Summary

For patients with a toothache, is pain relief after root canal procedure improved using long acting local anesthetic and analgesics? The purpose of this clinical trial is the investigate the effect of long acting local anesthetic with 1 of 4 oral medication groups, on post-operative endodontic pain.

Clinical Trial Description

Patients (n=220) presenting to the University of Minnesota Endodontic clinic, with moderate to severe pain from toothache requiring root canal treatment ,will be invited to participate in the study. The endodontic treatment is NOT part of the research. Patients will complete pain evaluation forms and take 2 doses of prescribed medication. Normally after a root canal procedure, patients will be suggested to take over-the-counter ibuprofen if needed, or prescribed an analgesic if they are having severe pain. We will be randomizing patients in double blind manner to receive regular or long acting local anesthesia and post-op medications (placebo or 1 of 3 analgesics), with the patient evaluating their pain before starting root canal (pre-treatment pain), after root canal, after analgesics and during the following day. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

• Odontalgia
• Toothache

• NCT number: NCT01982799
• Study type: Interventional
• Source: University of Minnesota - Clinical and Translational Science Institute
• Status: Withdrawn
• Phase: N/A
• Start date: February 2014
• Completion date: September 2015