Pediatric Pain Optimization After Tonsillectomy

Status Completed

Clinical Trial Summary

The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery.

Clinical Trial Description

This is a single center, randomized, double blind, parallel-group dose escalation investigation which will compare post operative pain control indices for patients receiving short acting versus long acting opioids as intraoperative analgesics. Surgical and anesthesia care, except for intraoperative opioid management, are not altered for study purposes. Subjects are randomized 2:1 to either long-duration (methadone) or short-duration opioid (fentanyl, hydromorphone) through the perioperative period. Exploratory data will be collected for up to 30 days post-operatively. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05244226
Study type	Interventional
Source	Duke University
Contact
Status	Completed
Phase	Phase 2
Start date	April 8, 2022
Completion date	May 10, 2023

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