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  3. NCT05458193

A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused Breath During Sleep

Obstructive Sleep Apnea of Adult Clinical Trial

Official title:
A Randomized, Double-blind, Placebo-controlled, 2-way Crossover Study to Investigate the Effects of Daridorexant on Nighttime Respiratory Function and Sleep in Patients With Severe Obstructive Sleep Apnea

Clinical Trial Summary

A study on the effects of daridorexant on nighttime respiratory function in patients with severe obstructive sleep apnea (OSA).

Clinical Trial Description

Each subject will participate in 2 study periods. Participants will receive 50 mg daridorexant in one period and placebo in the other period. Both periods will last from Day 1 (first administration) in the evening to Day 6 in the morning (defined as End-of-Period). The 2 periods will be separated by an in-between period of 1 to 2 weeks. An End-of-Study examination will take place 1 to 2 weeks after last administration of study treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05458193
Study type Interventional
Source Idorsia Pharmaceuticals Ltd.
Contact
Status Completed
Phase Phase 1
Start date August 17, 2022
Completion date February 28, 2023
View Details
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