The Effects of Weight Loss on Psoriatic Arthritis

Obesity Clinical Trial

Official title:

The Effect of Body Weight Management and Cognitive Exercise Therapy Approach on Psoriatic Arthritis Symptoms

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05393141
• Other study ID #: HU-SO-2022
• Status: Completed
• Phase: N/A
• Start date: January 30, 2022
• Est. completion date: October 15, 2022

Study information

• Verified date: December 2022
• Source: Hacettepe University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. This study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach (BETY-Bilişsel Egzersiz Terapi Yöntemi) interventions on symptoms. Accordingly, 45 overweight/obese subjects with PSA aged 20-65 years will divide into "diet", "diet+bety", and "control" groups. Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at the end of the study.

Description:

Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. The present study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach interventions on symptoms.

• Fourt-five overweight/obese subjects with PSA aged 20-65 years will divide into diet (n=15), diet+bety (n=15), and control (n=15) groups.

• Individually diet programs will be applied according to the metabolic, biochemical, and physical activity status of the subjects prepared by a registered dietitian.

• BETY exercise training will be given by a registered physiotherapist.

• The subjects will be followed for 12 weeks.

• Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at study completion.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 48
• Est. completion date: October 15, 2022
• Est. primary completion date: August 15, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 65 Years

Eligibility

Inclusion Criteria:

• overweight/obese

• diagnosed with PSA

Exclusion Criteria

• pregnancy or lactation

Related Conditions & MeSH terms

• Arthritis
• Arthritis, Psoriatic
• Obesity
• Psoriatic Arthritis

Intervention

Behavioral:
• diet and biopsychosocial exercise intervention
dietary intervention: biopsychosocial exercise intervention:

Locations

Country	Name	City	State
Turkey	Sümeyra Öteles	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Hacettepe University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Weight Loss	BMI (kilogram/metre2(kg/m2))	At the end of 3 months
Primary	DAPSA score	The score ranges from 0 to 50 points, with increased score reflect more discomfort	At the end of 3 months
Secondary	Quality of Life Score	The score ranges from 0 to 100 points, with increased score reflecting improved quality of life	At the end of 3 months