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Effects of XW003 Versus Liraglutide on Body Weight of Adult Participants With Obesity

Obesity Clinical Trial

Official title:
A Phase 2, Open-label, Randomised, Dose-Finding Study of XW003, Once-Weekly Human Glucagon-Like Peptide 1 Analogue, Compared With Once-Daily Liraglutide 3 mg in Adult Participants With Obesity

Clinical Trial Summary

XW003 is an acylated human glucagon-like peptide 1 (GLP-1) analogue and is being developed for type 2 diabetes mellitus (T2DM) and obesity management.

Clinical Trial Description

The study treatment period for 4 groups in the study will be divided into the four Titration Treatment periods and one Core Treatment period. The overall duration of the study treatment for each group will be 26 weeks. The duration of Titration Treatment will be up to 14 weeks for the three groups of XW003 treatment but 4 weeks for Saxenda group. Approximately 250 participants who are adults with obesity, in the absence of type 2 or any other type of diabetes, are planned to be screened. Based on a 20% screening failure rate, a total of 200 participants are expected to be enrolled for the four groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05111912
Study type Interventional
Source Sciwind Biosciences APAC CO Pty. Ltd.
Contact
Status Completed
Phase Phase 2
Start date November 30, 2021
Completion date December 20, 2022
View Details
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