Obesity Among Young Adult Males Born With Cesarean Section.

Obesity Clinical Trial

Official title:

Elective and Non-elective Cesarean Section and the Risk for Obesity Among Young Male Conscripts: a Population-based Cohort and Matched-sibling Analysis.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03918044
• Other study ID #: 20190405
• Status: Completed
• Start date: April 30, 2019
• Est. completion date: August 30, 2019

Study information

• Verified date: August 2019
• Source: Karolinska Institutet
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Previous research has suggested that cesarean section may be associated with an increased risk of developing obesity in childhood, adolescence and adulthood. Yet, previous studies have been small or unable to differentiate between elective and non-elective cesarean section. Therefore, using a population-based cohort the purpose is to examine the associations between vaginal delivery, elective and non-elective cesarean section on the risk of developing obesity in young adulthood among Swedish young singleton males. Using the Swedish medical birth registry, the recorded mode of delivery and indication of delivery which will be matched to those males who perform military conscription, where their body mass index is recorded. The investigators hypothesize that there will be an elevated risk of obesity in those born with non-elective cesarean section, as a function of confounding, while those born with elective cesarean section will not have a higher risk of obesity than those born with vaginal delivery.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 97291
• Est. completion date: August 30, 2019
• Est. primary completion date: August 1, 2019
• Accepts healthy volunteers: No
• Gender: Male
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Singleton birth.

• Retrievable from medical birth registry.

Exclusion Criteria:

• No available information on mode of delivery.

• Not conscripted.

• Extreme values at conscription.

Related Conditions & MeSH terms

• Caesarean Section
• Cesarean Section Complications
• Obesity

Locations

Country	Name	City	State
Sweden	Karolinska Institutet	Stockholm

Sponsors (1)

Lead Sponsor	Collaborator
Karolinska Institutet

Country where clinical trial is conducted

Sweden, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Categories of body mass index	World health organisation categories of body mass index: underweight BMI<18.5, normal weight BMI 18.5-24.9, overweight BMI 25-29.9 and obese BMI>30. Weight at conscription was measured using standardized scales and height was assessed using stadiometers in a standardized manner.	Measured at conscription (~18 years of age)
Secondary	Continuous body mass index	Measured continuous body mass index	Measured at conscription (~18 years of age)