Obesity Clinical Trial
Official title:
MRI Fat Quantification of the Liver, Subcutaneous and Visceral Fatty Tissue in Patients Before and After Bariatric Surgery
Verified date | July 2017 |
Source | University Hospital, Basel, Switzerland |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Fatty liver in the obese is a common finding; some cases develop steato-hepatosis which in the long-term can lead to liver cirrhosis. The effect of bariatric surgery on fat distribution in the liver has so far been studied with liver biopsies and single voxel MR techniques. With this trial investigators present a new, whole organ MR-quantification of liver fat and describe changes after bariatric surgery in visceral and subcutaneous fat.
Status | Completed |
Enrollment | 15 |
Est. completion date | July 2017 |
Est. primary completion date | July 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 60 Years |
Eligibility |
Inclusion Criteria: - morbidly obese patients with BMI over 35, scheduled for bariatric surgery (either sleeve gastrectomy or gastric bypass) Exclusion Criteria: - Smoking - substance abuse - Diabetes - history of gastrointestinal disorders - pace-maker - claustrophobia |
Country | Name | City | State |
---|---|---|---|
Switzerland | University Hospital | Basel |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Basel, Switzerland |
Switzerland,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Liver fat quantification | change in fat quantification; measurement of fat rate in the organ | within 3, 6 and 12 months of surgery | |
Secondary | Visceral fat quantification | change in fat quantification visceral; 2-point Dixon technique for volumetric fat imaging | within 3, 6 and 12 months of surgery | |
Secondary | Subcutaneous fat quantification | change in fat quantification subcutaneous; 2-point Dixon technique for volumetric fat imaging | within 3, 6 and 12 months of surgery |
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