The Interaction Between Appetite Hormones

Obesity Clinical Trial

Official title:

The Interaction Between Appetite Hormones and Their Importance for Maintenance of Weight Loss After a Low Calorie Diet

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02094183
• Other study ID #: H-4-2010-134
• Status: Completed
• Phase: N/A
• First received: March 17, 2014
• Last updated: July 4, 2014
• Start date: September 2011
• Est. completion date: April 2014

Study information

• Verified date: July 2014
• Source: University of Copenhagen
• Contact: n/a
• Is FDA regulated: No
• Health authority: Denmark: The Regional Committee on Biomedical Research EthicsDenmark: Danish Dataprotection Agency
• Study type: Interventional

Clinical Trial Summary

Glucagon Like Peptide (GLP) -1 affects metabolic response corrected for weight change

Description:

Many obese people have had several successful weight losses, however very few can maintain the weight loss over a longer period (e.g. one year) Therefore, we want to investigate the metabolic response and the importance for maintenance of weight loss in obese people, who lost at least 7, 5 % body weight by low calorie diet followed by 52 weeks of diet weight maintenance with or without supplement of GLP-1.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 58
• Est. completion date: April 2014
• Est. primary completion date: April 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 64 Years

Eligibility

Inclusion Criteria:

• BMI > 30 and < 40 (kg/m2)

• Healthy

Exclusion Criteria:

• Other known illness

• Medicine that affects glucose- and lipid metabolism, appetite or food intake

• Pregnancy

• Breast feeding

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Obesity

Intervention

Other:
• GLP-1
GLP-1

Dietary Supplement:
• low calorie diet
low calorie diet

Locations

Country	Name	City	State
Denmark	University of Copenhagen	Copenhagen
Denmark	Hvidovre University Hospital	Hvidovre

Sponsors (2)

Lead Sponsor	Collaborator
University of Copenhagen	The Danish Medical Research Council

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in hormone level corrected for weight change		Baseline and week 52	No