Obesity Clinical Trial
Official title:
Evaluation of Pulse Fibre Supplementation in Obesity and the Metabolic Syndrome: Generating Evidence in Support of Health Claims
The recent dramatic increase in obesity has been linked to a reduction of dietary fibre intake. We hypothesized that supplementing the diet of overweight and obesity adults with pulse fibre will improve their metabolic status, chiefly defined as greater weight loss. Other metabolic health improvements may include improved glucose control and reduced inflammatory markers.
The main objective of our study is to assess the effects of pulse fibre supplementation on
weight loss in an overweight and obese adult population.
Primary objective - To determine the effects of a 12 week intake of 15g/day of pea hull fibre
on weight loss supported by body composition measures.
Secondary objective - To measure glucose control and appetite regulation in overweight and
obese adults consuming 15g/day of pea hull fibre compared to a placebo control with the use
of plasma HbA1c and an oral glucose tolerance test (OGTT).
Tertiary objective - To examine mechanisms of action of pulse fibre supplementation by
determining the impact of pulse fibre supplementation on gut microbiota, serum metabolomics
and fecal short-chain fatty acid and bile acid concentrations.
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